TABLE 1.
Characteristics | Total (n = 807) | Women (n = 279) | Men (n = 528) | p-value |
Demographics | ||||
Age, years, median (P5–P95)a | 59 (35–81) | 62 (35–83) | 59 (35–80) | 0.002 |
Age category, n (%)b | 0.003 | |||
≤50 years | 196 (24.3) | 58 (20.8) | 138 (26.2) | |
51–65 years | 352 (43.6) | 110 (39.4) | 242 (45.8) | |
≥65 years | 259 (39.1) | 111 (39.8) | 148 (28.0) | |
BMI, kg/m2, median (P5-P95)a | 28.9 (22.9–40.9) | 30.5 (23.0–42.2) | 28.4 (22.8–39.2) | <0.001 |
BMI category, n (%)b | 0.004 | |||
Normal weight | 126 (15.6) | 37 (13.3) | 89 (16.9) | |
Overweight | 329 (40.8) | 98 (35.1) | 231 (43.7) | |
Obesity | 352 (43.6) | 144 (51.6) | 208 (39.4) | |
Comorbidities presence | ||||
Tobacco smoking, yes, n (%)b | 246 (30.5) | 50 (17.9) | 196 (37.1) | <0.001 |
T2D, yes, n (%)b | 232 (28.8) | 91 (32.6) | 141 (26.7) | 0.080 |
Hypertension, yes, n (%)b | 304 (37.7) | 117 (41.9) | 187 (35.5) | 0.072 |
PCRD, yes, n (%)b | 60 (7.5) | 30 (10.7) | 30 (5.7) | 0.009 |
Clinical characteristics | ||||
Symptoms onset days, median (P5-P95)a | 10 (4–21) | 9 (3–20) | 10 (4–21) | 0.002 |
Hospitalization days, median (P5-P95)a | 22 (8–68) | 21 (8–64) | 22 (9–68) | 0.436 |
IMV, yes, n (%)b | 665 (82.4) | 217 (77.8) | 448 (84.9) | 0.012 |
PaO2/FiO2 ratio, n (%)b | 0.541 | |||
>200 | 138 (17.1) | 45 (16.1) | 93 (17.6) | |
101–200 | 459 (56.9) | 155 (55.6) | 304 (57.6) | |
≤100 | 210 (26.0) | 79 (28.3) | 131 (24.8) | |
Outcome, n (%)b | 0.120 | |||
Survival | 491 (60.8) | 180 (64.5) | 311 (58.9) | |
Non-survival | 316 (39.2) | 99 (35.5) | 217 (41.1) |
BMI, body mass index; IMV, invasive mechanic ventilation; PCRD, previous chronic respiratory disease; T2D, type 2 diabetes.
aData are expressed as the median and percentiles 5th–95th, compared using Mann Whitney U-test.
bData are expressed as the n (%), compared using the Chi-square test.
p-value < 0.05 was considered statistically significant.