Table 2.

Multivariate analysis for overall and cancer-related survival.

	Overall survival		Cancer-related survival
	Hazard ratio (95% CI)	P value	Hazard ratio (95% CI)	P value
Age
<65	1 (reference)		1 (reference)
65-69	0.95 (0.54-1.67)	0.87	0.86 (0.45-1.66)	0.66
70-74	1.75 (1.06- 2.89)	0.03	1.54 (0.84-2.82)	0.16
75-79	2.00 (1.21-3.33)	0.007	1.59 (0.83-3.01)	0.16
80-84	4.39 (2.70-7.16)	< 0.001	1.99 (0.97-4.08)	0.06
85-89	4.36 (2.28-8.33)	< 0.001	1.66 (0.56-4.98)	0.36
Gender (male)	1.03 (0.75-1.41)	0.83	0.96 (0.64-1.44)	0.84
Tumour location
Left colon	1 (reference)		1 (reference)
Right colon	0.95 (0.65-1.37)	0.76	1.04 (0.62-1.74)	0.87
Rectum	0.89 (0.52-1.51)	0.66	0.92 (0.47-1.79)	0.81
Comorbidity (yes)	1.72 (1.12-2.66)	0.01	1.33 (0.81-2.18)	0.25
Type of surgery (urgent)	1.00 (0.46-2.03)	0.95	0.69 (0.21-2.32)	0.55
Postoperative complications (yes)	1.49 (1.09-2.03)	0.01	1.44 (0.96-2.15)	0.07
Stage
Stage 0-1	1 (reference)		1 (reference)
Stage 2	2.25 (1.39-3.64)	0.001	2.98 (1.43-6.23)	0.004
Stage 3	5.09 (3.08-8.42)	< 0.001	9.26 (4.48-19.13)	< 0.001
Stage 4	8.06 (3.99-16.28)	< 0.001	13.14 (5.28-32.69)	< 0.001
Potentially curative (R0-1)	0.29 (0.16-0.54)	< 0.001	0.25 (0.13-0.49)	< 0.001
Number of retrieved lymph-nodes <12	1.73 (1.34-2.64)	0.01	1.71 (1.00-2.92)	0.001
Neo-adjuvant therapy (yes)	2.09 (1.18-3.69)	0.01	2.82 (1.43-5.56)	0.003
Adjuvant therapy (yes)	0.69 (0.43-1.10)	0.12	0.67 (0.39-1.15)	0.15

p values – 0.05 were highlighted in bold.