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. 2022 Oct 21;9:1025557. doi: 10.3389/fsurg.2022.1025557

Figure 5.

Figure 5

The timeline of some key discoveries in the field of the skin disease using proteomics. The first records of proteomics used in several diseases and their subsequent development are listed here. We selected primary skin diseases that began in different periods to list and used high-impact factor articles as developing nodes to display in the follow-up development process AD, atopic dermatitis; SLE, systemic lupus erythematosus; AE, atopic eczema; PKP1, plakophilin-1; HAPLN1, hyaluronan and proteoglycan link protein 1; AXL, AXL receptor tyrosine kinase; YAP1, yes-associated protein 1; MITF, microphthalmia-associated transcription factor: DM, diabetes mellitus; KLK7, kallikrein-7.