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Development of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-EAE mice. (C) Colitis score was evaluated by immunopathological analysis in non-EAE (n = 11) and EAE mice (n= 10) as described in materials and methods. Mean ± SEM. ****P <0.0001.
