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. 2022 Oct 21;13:1015372. doi: 10.3389/fimmu.2022.1015372

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Copyright © 2022 Yadav, Ito, Mindur, Kumar, Youssef, Suresh, Kulkarni, Rosario, Balashov, Dhib-Jalbut and Ito

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fecal calprotectin and elastase levels in HDs and RRMS patients. (A, B) Fecal calprotectin levels (A) and fecal elastase levels (B) in RRMS (n = 14) and HDs (n = 18) are shown. (C, D) The levels of fecal calprotectin (C) and fecal elastase (D) in HDs, MS Lcn-2-low (<50 ng/mg total protein), and MS Lcn-2-high (>50 ng/mg total protein) subjects are shown. (E, F) Spearman correlation between fecal Lcn-2 and fecal calprotectin (E) or fecal elastase (F) is shown. HDs (n=18), MS Lcn-2-low (n=8), and MS Lcn-2-high (n=6). Mean ± SEM. *P < 0.05.