Table 5.
Comparison of RNFL thickness, CSA of TN, and the combined index in the diagnosis of DPN.
| AUC | Confidence interval | Cutoff value | Sensitivity | Specificity | ||
|---|---|---|---|---|---|---|
| RNFL thickness | Overall average | 0.675 | 0.587–0.755 | 103.50 | 0.713 | 0.690 |
| Superior quadrant | 0.723 | 0.645–0.805 | 127.50 | 0.705 | 0.721 | |
| Inferior quadrant | 0.686 | 0.599–0.765 | 138.50 | 0.591 | 0.762 | |
| CSA of TN | At 1 cm | 0.584 | 0.497–0.667 | 20.50 | 0.420 | 0.784 |
| At 3 cm | 0.617 | 0.530–0.698 | 18.50 | 0.440 | 0.809 | |
| At 5 cm | 0.660 | 0.575–0.739 | 13.50 | 0.820 | 0.416 | |
| Combined index | 0.755 | 0.664–0.846 | 0.376 | 0.643 | 0.830 | |
RNFL, retinal nerve fiber layer; CSA, cross-sectional area; TN, tibial nerve; DPN, diabetic peripheral neuropathy; AUC, area under the curve.