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. 2022 Oct 21;13:938659. doi: 10.3389/fendo.2022.938659

Table 5.

Comparison of RNFL thickness, CSA of TN, and the combined index in the diagnosis of DPN.

AUC Confidence interval Cutoff value Sensitivity Specificity
RNFL thickness Overall average 0.675 0.587–0.755 103.50 0.713 0.690
Superior quadrant 0.723 0.645–0.805 127.50 0.705 0.721
Inferior quadrant 0.686 0.599–0.765 138.50 0.591 0.762
CSA of TN At 1 cm 0.584 0.497–0.667 20.50 0.420 0.784
At 3 cm 0.617 0.530–0.698 18.50 0.440 0.809
At 5 cm 0.660 0.575–0.739 13.50 0.820 0.416
Combined index 0.755 0.664–0.846 0.376 0.643 0.830

RNFL, retinal nerve fiber layer; CSA, cross-sectional area; TN, tibial nerve; DPN, diabetic peripheral neuropathy; AUC, area under the curve.