Figure 3.

Chordoma tumor parenchymal T cell inclusion versus exclusion. T cell compartment inflammation in chordoma more commonly takes on a tumor parenchymal exclusion, rather than inclusion, pattern (n = 57 individual tumors). (A) A tumor:stroma T cell infiltrate ratio >1.5 defined substantial tumor parenchymal inclusion. A stroma:tumor T cell infiltrate ratio >4.5 defined substantial tumor parenchymal exclusion. (B) Representative chordoma samples with heavy tumoral infiltrate (left) versus heavy stromal infiltrate (right).