Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 21;12:1012058. doi: 10.3389/fonc.2022.1012058

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Lopez, Robbins, Kowalczyk, Lassoued, Gulley, Miettinen, Gallia, Allen, Hodge and London

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Spatial characterization of distance between Tregs to proliferating and nonproliferating CD8+ T cells in chordoma tumor slides (n = 57). Percentage of Tregs within 20µm of nonproliferating CD8+ T cells (mean 8.90 ± SEM 1.74) is significantly greater than that within 20µm of proliferating CD8+ T cells (mean 1.34 ± SEM 0.57) (p < 0.0001), shown above. A Wilcoxon signed rank test with a p value threshold of <0.05 was used. ****p ≤ 0.0001. Proximity analysis histograms of Tregs within a 20µm radius of nonproliferating CD8+ T cells (left, blue) and proliferating CD8+ T cells (right, red) by progressive segments of 1µm bands, shown below.