Table 3.
Moderator | N studies | HR | 95% CI | Heterogeneity I2 (%) | z-score | P-value | |
---|---|---|---|---|---|---|---|
RCTs | |||||||
Including15 (active comparator) | 11 | 0.94 | 0.71 | 1.25 | 64 | 0.41 | .68 |
Active control instead of inactive for16 | 10 | 0.83 | 0.71 | 0.98 | 0 | 2.21 | .03 |
Including15 and active control for16 | 11 | 0.96 | 0.73 | 1.28 | 66 | 0.26 | .79 |
uME compared to no therapy instead of chemo for17 | 10 | 0.8 | 0.68 | 0.94 | 0 | 0.267 | .008 |
NRSIs | |||||||
Including14 (prospective NRSIs, active comparator) | 8 | 0.68 | 0.45 | 1.03 | 88 | 1.8 | .07 |