TABLE 4.
Distribution of levels of protein markers of inflammation according to category of infection
| Marker | Median concna (interquartile range)
|
Kruskal-Wallis P value | ||
|---|---|---|---|---|
| Category 1 | Category 2 | Category 3 | ||
| Albumin (mg/ml) | 50.0 (45.0–59.2) | 50.0 (38.6–60.9) | 52.6 (45.0–63.0) | NSb |
| CRP (μg/ml) | 7.9 (4.0–21.8) | 4.0 (0.0–9.5) | 0.0 (0.0–7.2) | 0.05 |
| Ferritin (ng/ml) | 121.2 (68.2–158.7) | 87.4 (35.7–147.5) | 43.6 (29.1–103.1) | 0.004 |
| ECP (ng/ml) | 75 (48–150) | 50 (36.5–70) | 59 (49.5–75.7) | 0.028 |
| hsp27 | 0.175 (0.11–0.34) | 0.215 (0.09–0.42) | 0.48 (0.13–0.76) | 0.04 |
| hsp60 | 0.596 (0.37–1.34) | 0.782 (0.32–1.67) | 1.127 (0.54–1.45) | NS |
| hsp90 | 0.501 (0.37–0.79) | 0.575 (0.43–0.75) | 0.636 (0.49–1.03) | 0.077 |
a
Measured as described in Materials and Methods. Normal values for Caucasian children: albumin, 37 to 56 mg/ml; CRP, <10 μg/ml; ferritin, 37 to 142 ng/ml; ECP, 2.3 to 16 ng/ml (reference 47 and Yorkhill Children’s Hospital, Glasgow, biochemistry values). The anti-heat shock protein responses are expressed in arbitrary optical density units.
b
NS, not significant.