Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 21;13:1035380. doi: 10.3389/fgene.2022.1035380

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Drekolia, Talyan, Cordellini Emídio, Boon, Guenther, Looso, Dumbović and Bibli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of aging on endothelial cell transcriptome. Bulk RNA-sequencing analysis was performed in human native young and aged arterial endothelial cells (n=6 per group, each sample is a pool of 5 different isolates). (A,C) Hierarchical clustering heatmap showing differentially expressed mRNAs (A) and lncRNAs (C). (B,D) Representative volcano plots showing differentially expressed mRNAs (B) and lncRNAs (D) (total mRNA variables = 15,379, total lncRNA variables = 4,463). (E) Chromosome distribution of differentially expressed (DE) lncRNAs detected as in (C) and (D). (F) Expression levels presented as ΔFPKM of lncRNA transcripts detected in panels (C) and (D).