TABLE 2.
Prediction model for all-cause death (n = 107).
| HALO (Hfpef survivAL hOspitalization) prediction model | |||
|
| |||
| Variables | Hazard ratio | Confidence interval | P-value |
| Age (years) | 1.024 | 0.997–1.051 | 0.081 |
| Body mass index (kg/m2) | 0.971 | 0.934–1.008 | 0.124 |
| NYHA functional class | 1.761 | 1.197–2.588 | 0.004 |
| Use of loop diuretic therapy | 1.589 | 0.980–2.576 | 0.061 |
| LA volume index (ml/m2) (IQR) | 1.012 | 1.000–1.025 | 0.048 |
| Pulmonary arterial systolic pressure (mmHg) | 1.013 | 1.003–1.022 | 0.013 |
| NT-proBNP/100 (pg/ml) | 1.054 | 0.995–1.116 | 0.076 |
| Category of HF† hospitalizations | 1.481 | 1.115–1.968 | 0.006 |
NYHA, New York Heart Association; LA, left atria; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; HF, heart failure.
†HF hospitalizations were categorized in no, one and more than one episode defined by the concomitant presence of the symptom of sudden-onset dyspnea and clinical signs of acute cardiac decompensation, including weight gain and fluid retention, with presence of pulmonary or peripheral edema requiring intravenous diuresis.