Table 2. Multivariate Logistic Regression for Bilateral Mastectomy.
| Variable | OR (95% CI) | |
|---|---|---|
| Unadjusted | Adjusted | |
| Age at first breast cancer diagnosis, y | ||
| <50 | 2.97 (2.03-4.35) | 2.21 (1.44-3.40) |
| ≥50 | 1 [Reference] | 1 [Reference] |
| Timing of genetic testing | ||
| Before surgery | 6.65 (4.45-9.92) | 5.79 (3.83-8.76) |
| After surgery | 1 [Reference] | 1 [Reference] |
| Family history of breast cancer | ||
| No family history | 1 [Reference] | 1 [Reference] |
| First-degree relative | 0.89 (0.53-1.48) | 1.03 (0.57-1.87) |
| Second-degree relative | 1.05 (0.59-1.84) | 0.99 (0.52-1.88) |
| Third-degree relative | 0.58 (0.26-1.28) | 0.63 (0.25-1.56) |
| Gene with variant | ||
| BRCA1 or BRCA2 | 1 [Reference] | 1 [Reference] |
| ATM | 1.45 (0.66-3.18) | 1.62 (0.66-3.95) |
| CHEK2 | 0.97 (0.53-1.78) | 1.23 (0.63-2.42) |
| PALB2 | 1.03 (0.63-1.67) | 1.32 (0.76-2.29) |
Abbreviation: OR, odds ratio.