Figure 5.

Reduction of office and 24-h systolic blood pressure (SBP) in the hypertensive patients of the ELSA trial (European Lacidipine Study on Atherosclerosis) treated with antihypertensive drugs for 4 y. SBP was measured at narrow intervals during the initial titration phase and then at intervals of 6 mo. Grey histograms refer to sustained hypertensive patients and white histograms to white-coat hypertensive (WCH). The right panels show the relationship between the treatment-induced reduction of office or 24-h SBP and the corresponding baseline values. White points indicate WCH patients and grey points, sustained hypertensive (SH) patients. Statistical significance between groups are shown by the following symbols: *P<0.05, ΔP<0.01, † and ‡P<0.0001 vs control. WCH indicates white-coat hypertension. Data derived from Mancia et al.⁶¹