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. 2022 Jul 11;13:936106. doi: 10.3389/fimmu.2022.936106

Table 1.

Anthropometric and clinical characteristics of the studied population.

Healthy n = 31 Mild n = 152 Severe n = 60 Critical n = 210 P value
Age (years) & 43 (32,52) 42 (31,49) 51.5 (44,63.5) 57(49,67) <0.001**
Male gender, n (%) 17 (55) 73 (48) 33 (55) 144(69) 0.001*
Heart rate, median (IQR), bpm+& 85 (73,102) 87 (78,103) 90 (80,103) 95 (88,110) <0.001**
Body temperature, median (IQR) &, °C 36.3 (36.3,36.45) 36.35 (36.1,36.5) 37 (36.4,38) 36.5 (36.1,37.1) <0.001**
Oxygen saturation % (IQR) & 95 (94,97) 94 (93,96) 88 (80,92) 83 (71,88) <0.001**
Breathing frequency, median (IQR), bpm+& 16 (15,16.5) 18 (16,20) 18 (17,20) 28 (24,36) <0.001**
WHO body mass index classification, n (%)
 Normal weight 17 (55) 115 (76) 20 (33) 37 (18) <0.001*
 Overweight 11 (35) 21 (14) 22 (37) 88 (42)
 Obesity 3 (10) 16 (10) 18 (30) 85 (40)
T2DM, n (%) 3 (13) 13 (8) 21 (35) 74 (35) <0.001*
Hypertension, n (%) 4 (17) 11 (7) 15 (25) 85 (41) <0.001*
Fever, n (%) 0 (0) 47 (31) 29 (48) 116 (57) <0.001*
Cough, n (%) 5 (16) 90 (59) 44 (73) 171 (81) <0.001*
Dyspnea, n (%) 1 (3) 39 (26) 43 (72) 152 (72) <0.001*
Chest pain, n (%) 1 (3) 37 (24) 19 (36) 60 (30) 0.006*
Headache, n (%) 3 (10) 95 (62) 30 (50) 125 (59) <0.001*
Odynophagia, n (%) 0 (0) 74 (49) 29 (48) 82 (39) <0.001*
Rhinorrhea, n (%) 4 (13) 67 (44) 9 (15) 42 (20) <0.001*
Myalgia, n (%) 0 (0) 78 (67) 24 (57) 113 (54) <0.001*
Diarrhea, n (%) 2 (6) 37 (24) 17 (28) 53 (25) 0.11*
Sickness, n (%) 1 (3) 33 (22) 3 (5) 104 (49) <0.001*
Vomiting, n (%) 0 (0) 6 (4) 4 (7) 22 (10) 0.09*
Abdominal pain, n (%) 0 (0) 18 (12) 8 (13) 25 (12) 0.82*
Anosmia, n (%) 0 (0) 33 (22) 13 (22) 24 (11) 0.004*

+Beats per minute; *Chi square test; **Kruskal-Wallis Test. IQR, interquartile range.

&Dunn post hoc test p<0.05. Age: Healthy vs Severe; Healthy vs. Critical; Mild vs. Sever; Mild vs. Critical; Severe vs. Critical.

&Dunn post hoc test p<0.05. Heart rate: Mild vs. Critical.

&Dunn post hoc test p<0.05. Body temperature: Healthy vs Severe; Mild vs. Sever; Mild vs. Critical; Severe vs. Critical.

&Dunn post hoc test p<0.05. Oxygen saturation: Healthy vs Severe; Healthy vs. Critical; Mild vs. Sever; Mild vs. Critical; Severe vs. Critical.

&Dunn post hoc test p<0.05. Breathing frequency: Healthy vs. Critical; Mild vs. Sever; Sever vs. Critical.