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(A) Western blotting of NLRP3, pro caspase-11, cleaved caspase-11, pro-caspase-1, cleaved caspase-1, and IL-1β. Relative expression of (B) NLRP3; (C) pro-caspase-11; (D) cleaved caspase-11; (E) pro-caspase-1; (F) cleaved caspase-1; and (G) IL-1β. Data are means±standard deviations (n=3). *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001. ALF, acute liver failure; Control, normal; DMSO, dimethyl sulfoxide; NSA, necrosulfonamide.
