Table 3. Features of randomized controlled trials evaluating the effect of polyphenol administration on rheumatic diseases.

Author	Country, year	Sample features	Intervention	Control group	Rheumatic disease	Outcome	Results after intervention
Hänninen, et al.31	Finland, 2000	115	Diet of living food*	Yes	Rheumatoid arthritis and fibromyalgia	Symptoms of rheumatoid arthritis and fibromyalgia	↓ rheumatoid arthritis activity (P = 0.03)
							Joint stiffness mitigation (P = 0.001)
							Pain mitigation (P = 0.003)
Bitler, et al.29	United States, 2007	90	400 mg/day of olive pulp	Yes	Osteoarthritis and rheumatoid arthritis	Ability to perform daily activities, disease activity and inflammation	↓ CRP (P < 0.01)

^*Diet of living food consisted of vegan diet without cooking; CRP = C-reactive protein.