Table 1.
The baseline characteristics of subjects in the Kailuan Cohort
| TyG index | |||||
|---|---|---|---|---|---|
| Characteristics | Total | Q1 | Q2 | Q3 | Q4 |
| 3.60–8.18 | 8.19–8.57 | 8.58–9.05 | 9.06–12.51 | ||
| Subjects (n) | 95,996 | 23,997 | 24,000 | 24,001 | 23,998 |
| TyG index | 8.65 ± 0.69 | 7.85 ± 0.27 | 8.38 ± 0.11 | 8.79 ± 0.14 | 9.58 ± 0.46 |
| Age, years | 51.4 ± 12.5 | 50.2 ± 13.7 | 51.4 ± 12.7 | 52.1 ± 12.2 | 52.0 ± 11.4 |
| Male, n (%) | 76,364(79.6) | 17,655(73.6) | 18,994(79.1) | 19,501(81.3) | 20,214(84.2) |
| Height (cm) | 167.4 ± 7.0 | 166.7 ± 7.0 | 167.5 ± 7.0 | 167.6 ± 7.0 | 167.9 ± 6.9 |
| BMI (kg/m2) | 25.0 ± 3.5 | 23.4 ± 3.2 | 24.6 ± 3.3 | 25.6 ± 3.3 | 26.4 ± 3.4 |
| Completed high school, n (%) | 18,746(19.5) | 5673(23.6) | 4483(18.7) | 4448(18.5) | 4142(17.3) |
| Income ≥ 800¥, n (%) | 13,133(13.7) | 3563(14.9) | 3093(12.9) | 3234(13.5) | 3243(13.5) |
| Daily Smoker, n (%) | 28,675(29.9) | 6902(28.8) | 6741(28.1) | 7173(29.9) | 7859(32.8) |
| Daily alcohol user, n (%) | 16,725(17.4) | 3891(16.2) | 3834(16.0) | 4125(17.2) | 4875(20.3) |
| Activity physical activity, n (%) | 13,935(14.5) | 3654(15.2) | 3356(14.0) | 3535(14.7) | 3390(14.1) |
| Systolic BP, mmHg | 131 ± 21 | 124 ± 20 | 129 ± 20 | 132 ± 21 | 136 ± 21 |
| Diastolic BP, mmHg | 83 ± 12 | 80 ± 11 | 83 ± 11 | 85 ± 1 | 87 ± 12 |
| FBG, mmol/L | 5.47 ± 1.67 | 4.80 ± 0.68 | 5.09 ± 0.76 | 5.44 ± 1.11 | 6.54 ± 2.66 |
| TC, mg/dL | 190.9 ± 44.1 | 179.3 ± 35.6 | 190.2 ± 37.3 | 197.9 ± 39.0 | 196.4 ± 58.1 |
| LDL-c, mg/dL | 90.6 ± 35.2 | 84.3 ± 35.8 | 92.2 ± 33.3 | 94.7 ± 33.99 | 91.2 ± 36.7 |
| HDL-c, mg/dL | 59.8 ± 15.5 | 60.5 ± 15.7 | 60.3 ± 14.8 | 59.3 ± 15.1 | 59.0 ± 16.3 |
| TG, mg/dL |
112.4 (78.8-170.8) |
62.0 (51.3–72.6) |
97.4 (86.7–108.0) |
137.2 (120.4-158.4) |
245.1 (192.9–346.0) |
| hs-CRP, mg/dl |
0.80 (0.30–2.16) |
0.60 (0.21–1.84) |
0.72 (0.29–1.99) |
0.88 (0.33–2.16) |
1.02 (0.40–2.61) |
| eGFR, mL/min/1.73m2 | 82.3 ± 25.7 | 85.8 ± 26.8 | 81.8 ± 25.4 | 81.4 ± 22.8 | 80.5 ± 27.2 |
| Diabetes Mellitus, n (%) | 8408(8.8) | 223(0.9) | 542(2.3) | 1699(7.1) | 5944(24.8) |
| Hypertension, n (%) | 4,1072(42.8) | 6847(28.5) | 9651(40.2) | 11,316(47.2) | 13,258(55.3) |
|
Anti-hypertensive drugs, n (%) |
9453(9.9) | 1440(6.0) | 1915(8.0) | 2714(11.3) | 3384(14.1) |
| Lipid-lowering drugs, n (%) | 709(0.7) | 81(0.3) | 130(0.5) | 168(0.7) | 330(1.4) |
| Diabetes drugs, n (%) | 2048(2.1) | 121(0.5) | 209(0.9) | 442(1.8) | 1273(5.3) |
Abbreviations: BMI: body mass index; BP: blood pressure; FBG: fasting blood glucose; TC: total cholesterol; LDL-c: low density lipoprotein cholesterol; HDL-c: low density lipoprotein cholesterol; TG: triglyceride; eGFR: estimated glomerular filtration rate; hs-CRP: high sensitivity C-reactive protein