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. 2022 Nov 1;38(1):176–191. doi: 10.1080/14756366.2022.2135512

Table 2.

The inhibitory potentials of the investigated 8 and 14 targets towards EGFR (Wild) and EGFR (T790M).

Compound EGFR IC50 (µM)
Wild T790M
8 0.131 ± 0.008 0.027 ± 0.002
14 0.203 ± 0.012 0.156 ± 0.009
Erlotinib 0.042 ± 0.003 0.009 ± 0.001