TABLE 4.
Plasmid stability in vivoa
Strain (plasmid) | % Kanr
|
||
---|---|---|---|
Day 1 | Day 3 | Day 7 | |
ΔANR(pPA102) | 108 ± 8b | 113 ± 38 | 70 ± 30 |
ΔSterne(pPA102) | 96 ± 8 | 98 ± 4 | 107 ± 9 |
ΔSterne(pJB2) | 98 ± 14 | 95 ± 21 | 127 ± 12 |
B. anthracis strains were inoculated on day 0 and isolated from the leg muscles of three guinea pigs at each time point for each strain and plated in the presence and absence of KAN to determine plasmid retention.
Values represent the mean ± the standard deviation from three animals.