TABLE 2.
Accuracy of DMI Indices in Cross-Validation on Training Cohort
| Diagnosis | Metrics | Overall | Short symptom duration (≤2 y) | Long symptom duration (>2 y) |
|---|---|---|---|---|
| IPD | AUC | 0.986 (0.977–0.996) | 0.981 (0.965–0.997) | 0.991 (0.981–1.000) |
| Sensitivity | 95.7% (92.7%–97.7%) | 94.9% (89.7%–97.9%) | 95.7% (91.4%–98.3%) | |
| Specificity | 97.6% (94.8%–99.1%) | 97.6% (93.1%–99.5%) | 98.4% (94.3%–99.8%) | |
| PPV | 97.9% (95.6%–98.9%) | 97.7% (93.5%–99.1%) | 98.7% (95.5%–99.5%) | |
| NPV | 94.9% (91.5%–98.1%) | 94.5% (89.1%–98.8%) | 94.6% (89.2%–99.3%) | |
| MSA | AUC | 0.997 (0.994–1.000) | 0.996 (0.988–1.000) | 0.998 (0.995–1.000) |
| Sensitivity | 97.3% (93.3%–99.3%) | 100% (96.0%–100%) | 98.3% (91.1%–100%) | |
| Specificity | 99.5% (98.2%–99.9%) | 98.2% (94.9%–99.6%) | 99.6% (97.6%–100%) | |
| PPV | 98.6% (95.3%–99.6%) | 96.8% (91.0%–100%) | 98.3% (91.3%–100%) | |
| NPV | 99.0% (97.4%–99.9%) | 100% (97.8%–100%) | 99.6% (97.5%–100%) | |
| PSP | AUC | 0.982 (0.965–0.998) | 0.968 (0.925–1.000) | 0.990 (0.980–1.000) |
| Sensitivity | 91.8% (84.5%–96.4%) | 88.2% (72.5%–96.7%) | 93.8% (84.8%–98.3%) | |
| Specificity | 98.2% (96.5%–99.2%) | 98.2% (95.5%–99.5%) | 98.2% (95.5%–99.5%) | |
| PPV | 91.8% (85.0%–96.4%) | 88.2% (74.3%–96.7%) | 93.7% (85.2%–98.3%) | |
| NPV | 98.2% (96.4%–99.2%) | 98.2% (95.1%–99.5%) | 98.2% (95.3%–99.5%) |
AUC = area under the curve.