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. 2022 Nov 4;17(11):e0273781. doi: 10.1371/journal.pone.0273781

Table 2. Probabilities with screening option.

date of maternal primary infection
Probabilities 12 Weeks 16 Weeks 20 Weeks 24 Weeks 28 Weeks 32 Weeks 36 Weeks* Newborn * Postnatal * References
Maternal IgG (+) (Seroprevalence) 0.313 [18]
IgG(+) IgM(+) Primary Maternal Infection 0.0016 [18]
Confirmation test (+) 0.9 [1]
Fetal death due to CT 0.02 0.0025 0 0 0 0 0 0 0 [30]
Fetal loss from amniocentesis 0.003 (0.0011–0.0049) 0.003 0.003 0.003 0 0 [31]
Amniocentesis (-) 0.90 0.873 0.785 0.638 0.514 0.450 [8, 24, 32]
False negative of amniocentesis (CT if amniocentesis (-)) 0.05 0.05 0.05 0.05 0.10 0.15 [8, 24, 32]
Asymptomatic CT if amniocentesis (-) 0.70 0.70 0.75 0.775 0.79 0.79 0.795 0.795 0.795 [8, 24, 32]
Visual injury if CT with amniocentesis (-) 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 [2, 12, 14, 33, 34]
Visual and cognitive injury if CT with amniocentesis (-) 0.10 0.10 0.05 0.025 0.01 0.01 0.005 0.005 0.005 [2, 12, 14, 33, 34]
Asymptomatic CT if amniocentesis (+) 0.50 0.5 0.70 0.75 0.795 0.795 [2, 12, 14, 33, 34]
Visual injury if CT with amniocentesis (+) 0.30 0.30 0.25 0.20 0.20 0.20 [2, 12, 14, 33, 34]
Visual and cognitive injury if CT with amniocentesis (+) 0.20 0.20 0.05 0.05 0.005 0.005 [2, 12, 14, 33, 34]

*Probability without amniocentesis and with confirmatory testing