Table 2. Probabilities with screening option.
date of maternal primary infection | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Probabilities | 12 Weeks | 16 Weeks | 20 Weeks | 24 Weeks | 28 Weeks | 32 Weeks | 36 Weeks* | Newborn * | Postnatal * | References |
Maternal IgG (+) (Seroprevalence) | 0.313 | [18] | ||||||||
IgG(+) IgM(+) Primary Maternal Infection | 0.0016 | [18] | ||||||||
Confirmation test (+) | 0.9 | [1] | ||||||||
Fetal death due to CT | 0.02 | 0.0025 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | [30] |
Fetal loss from amniocentesis | 0.003 (0.0011–0.0049) | 0.003 | 0.003 | 0.003 | 0 | 0 | [31] | |||
Amniocentesis (-) | 0.90 | 0.873 | 0.785 | 0.638 | 0.514 | 0.450 | [8, 24, 32] | |||
False negative of amniocentesis (CT if amniocentesis (-)) | 0.05 | 0.05 | 0.05 | 0.05 | 0.10 | 0.15 | [8, 24, 32] | |||
Asymptomatic CT if amniocentesis (-) | 0.70 | 0.70 | 0.75 | 0.775 | 0.79 | 0.79 | 0.795 | 0.795 | 0.795 | [8, 24, 32] |
Visual injury if CT with amniocentesis (-) | 0.20 | 0.20 | 0.20 | 0.20 | 0.20 | 0.20 | 0.20 | 0.20 | 0.20 | [2, 12, 14, 33, 34] |
Visual and cognitive injury if CT with amniocentesis (-) | 0.10 | 0.10 | 0.05 | 0.025 | 0.01 | 0.01 | 0.005 | 0.005 | 0.005 | [2, 12, 14, 33, 34] |
Asymptomatic CT if amniocentesis (+) | 0.50 | 0.5 | 0.70 | 0.75 | 0.795 | 0.795 | [2, 12, 14, 33, 34] | |||
Visual injury if CT with amniocentesis (+) | 0.30 | 0.30 | 0.25 | 0.20 | 0.20 | 0.20 | [2, 12, 14, 33, 34] | |||
Visual and cognitive injury if CT with amniocentesis (+) | 0.20 | 0.20 | 0.05 | 0.05 | 0.005 | 0.005 | [2, 12, 14, 33, 34] |
*Probability without amniocentesis and with confirmatory testing