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. 2022 Oct 22;13(5):299–310. doi: 10.14740/wjon1529

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Copyright 2022, Bai et al.

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Validation of the CRGs signature in the ICGC cohort. (a) Risk scores based on CRGs prognostic signatures (above), survival of HCC patients with high- or low-risk scores (middle), and expression of four CRGs that constitute the prognostic signature in the ICGC cohort (below). (b) PCA analysis of high- and low-risk scores in the ICGC cohort. (c) Kaplan-Meier plot of OS between high- and low-risk score groups in the ICGC cohort. (d) Time-dependent ROC curves for the prognostic performance of the CRGs signature in the ICGC cohort. (e, f) Univariate (e) and multivariate (f) Cox regression analyses regarding OS evaluated the prognostic value of the CRGs signature and other factors in the ICGC cohort. HR: hazard ratio.