Table 2. Demographics, EGD and CT findings, EGD and interventional radiology intervention, and clinical outcome of cases 6 to 10.
CT: computed tomography; GDA: gastroduodenal artery; IPDA: inferior pancreaticoduodenal artery; SMA: superior mesenteric artery.
Case 6 | Case 7 | Case 8 | Case 9 | Case 10 | |
Age (years) | 65 | 55 | 53 | 67 | 59 |
Gender | Male | Male | Male | Male | Male |
Presenting complaint | Melena | Hematemesis | Melena | Hematemesis | Hematochezia |
EGD findings | Few nonbleeding duodenal ulcers and one oozing duodenal ulcer with a visible vessel ( Forrest Ib) | Multiple dispersed nonbleeding erosions with no stigmata of recent bleeding, and one oozing cratered 30 mm duodenal ulcer (Forrest Ib) | One bleeding duodenal ulcer, one oozing duodenal ulcer (Forrest Ib) and one nonbleeding duodenal ulcer | Large friable necrotic, malignant-looking infiltrative bleeding mass in duodenum | One bleeding cratered duodenal ulcer with a visible vessel in the duodenal bulb (Forrest IIa) |
EGD intervention | Epinephrine injection and electrocautery | Epinephrine injection. Thermal therapy deferred due to risk of perforation | Clips placed | None | Epinephrine injection and electrocautery |
CT abdomen findings | Hyperdense material seen within the second portion of the duodenum | Dense-fluid-filled duodenal wall thickening and ulceration crater | Hypertrophic submucosal arterioles along the second portion of the duodenum | Infiltrative mass with active bleeding in the second part of the duodenum | Hypertrophic submucosal arterioles along the duodenum |
Angiogram findings | Irregularly tortuous duodenal arterioles as the culprit of bleeding from branch of the gastroduodenal artery (GDA) with hypertrophic inferior pancreaticoduodena artery (IPDA) shunting toward the superior mesenteric artery (SMA) | Many focal bleeding blush adjacent to endoscopic clip | Irregularly tortuous duodenal arterioles as the culprit of bleeding from branch of the GDA with shunting toward the SMA | Active duodenal bleeding from IPDA coming off GDA | irregular and spastic GDA with questionable focal bleeding blush adjacent to endoscopic clips |
Interventional radiology intervention | Particulate polyvinyl alcohol (PVA) 500 micron particle used in the GDA | 1 coil and 2 vascular plugs deployed along the GDA | Particulate PVA 500 micron particle used in the GDA | 5 coils deployed along IPDA beyond the takeoff of gastroepiploic artery | 1 coil and 2 vascular plugs deployed along the GDA |
Outcome | Expired - likely due to severe sepsis with septic shock secondary to pneumonia from multidrug-resistant gram-negative organism | Alive with no further known duodenal bleeding episodes after angioembolization | Expired - likely due to severe sepsis with septic shock secondary to multifocal pneumonia | Alive with no further known duodenal bleeding episodes after angioembolization | Expired - likely due to respiratory failure due to left lung collapse secondary to endobronchial lesion |