Table 2.

Subgroup analysis.

Subgroups	No. of Studies	RR (95% CI)	I2 (%)	Pinteraction (between subgroups)
Total Cancer Incidence
By Regimen Intake
Daily intake	8	0.98 (0.93–1.03)	0	0.38
Nondaily intake in a large bolus	4	1.05 (0.90–1.23)	0
By Attained 25(OH)D
>100 nmol/L	6	0.97 (0.90–1.04)	0	0.64
≤100 nmol/L	6	0.99 (0.93–1.06)	0
By baseline 25(OH)D
>50 nmol/L	9	0.96 (0.89–1.03)	0	0.55
≤50 nmol/L	2	1.00 (0.93–1.08)	20
Total Cancer Mortality
By Regimen Intake
Daily intake	4	0.87 (0.79–0.97)	0	0.05
Nondaily intake in a large bolus	3	1.06 (0.90–1.25)	8
By Attained 25(OH)D
>100 nmol/L	4	0.99 (0.80–1.23)	46	0.25
≤100 nmol/L	3	0.88 (0.79–0.98)	0
By baseline 25(OH)D
>50 nmol/L	5	0.97 (0.82–1.15)	34	0.16
≤50 nmol/L	2	0.88 (0.78–0.99)	0
By study population
Postmenopausal women	4	0.89 (0.73–1.08)	26	0.47
General population	5	1.01 (0.94–1.08)	0
Diseased population	3	0.97 (0.70, 1.34)	29