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. 2022 Nov 17;10:280. Originally published 2021 Apr 9. [Version 3] doi: 10.12688/f1000research.52439.3

Table 4. Definition of Close Contacts and Other Contacts.

Study ID Definitions of close contacts Definition of other contacts Contact duration & proximity
Abdulrahman 2020 Not defined Not reported Not reported
Adamik 2020 Not defined Other cases in each of the infected households were
regarded as secondary cases
Not reported
Afonso 2021 Not defined Essential activity workers with COVID‐19, confirmed by the
RT‐PCR, were considered the primary case (index cases)
at their households. Their respective infected household
contacts were defined as secondary case or secondary
transmission cases.
Not reported
Agergaard 2020 Not defined Not reported 2 weeks
Akaishi 2021 1) Contact with a COVID-19 patient between 2 days
before and 14 days after the onset of symptoms, 2) no
usage of masks, 3) distance less than 1 m, and 4) more
than 15 min of contact
Lower-risk contact was defined as being in the same place
as the COVID-19 patients, but without fulfilling the above-
described criteria for close contact.
<1m for >15 min
Angulo-Bazán 2021 Not defined Not reported Not reported
Armann 2021 Not defined Not reported Not reported
Arnedo-Pena 2020 Close contacts living in the same household of the
index case and no other sources of transmission apart
from the index case could be found.
Closed contacts from work, social events, relatives live in
other household were excluded and index cases live alone.
Not reported
Atherstone 2021 CDC definition: <6 feet away from someone with
suspected or confirmed COVID-19 for a cumulative
total of 15 minutes or more
over a 24-hour period
Not reported <1m for >15 min
Baettig 2020 Close contact: Less than 2 m for more than 15 min in
the last 48 hours before onset symptom of the
COVID-19 positive index patient.
Not reported <2m for >15 mins 48 hours
before onset symptom of the
COVID-19 positive index patient
Baker 2020 Not defined Not reported Median cumulative time spent
with the patient 45 mins (10–720
mins)
Bao 2020 Not defined Not reported Average stay duration of 2.5
hr daily before the COVID‐19
outbreak.
Basso 2020 Close contact: ≥15 min at ≤2 m, or during AGPs,
between HCWs and the non-isolated COVID-19 patient
Not reported ≤2 m for ≥15 min or during AGP
Bays 2020 Not defined Not reported Not specified
Bender 2021 Person with >15 minutes face-to-face contact within a
maximum distance of 2 m to the index case
Not reported <2m for >15min
Bernardes-Souza
2021
Not defined Not reported Not reported
Bhatt 2022 Not defined Household members: people residing in the same dwelling
as the index participant.
Not reported
Bi 2020 Close contacts were identified as those who lived
in the same apartment, shared a meal, travelled, or
socially interacted with an index case 2 days before
symptom onset.
Casual contacts (eg, other clinic patients) and some close
contacts (eg, nurses) who wore a mask during exposure
were not included in this group.
Not specified
Bi 2021 Not defined Not reported Not reported
Bistaraki 2021 Not defined Household contacts were defined as people who lived in
the same house with the confirmed SARS-CoV-2 patient.
Not reported
Bjorkman 2021 Not defined Not reported Not reported
Blaisdell 2020 Not defined Not reported 1 week
Böhmer 2020 High risk if they had cumulative face-to-face contact
with a patient with laboratory-confirmed SARS-CoV-2
infection for at least 15 min, had direct contact with
secretions or body fluids of a patient with confirmed
COVID-19, or, in the case of health-care workers, had
worked within 2 m of a patient with confirmed
COVID-19 without PPE
All other contacts were classified as low-risk contacts. Face-to-face for at least 15
minutes, direct contact without
PPE
Boscolo-Rizzo 2020 Not defined Not reported Not reported
Brown 2020 Not defined Not reported Mean in-class time = 50 minutes
Burke 2020 Either at least 10 minutes spent within 6 feet of the
patient with confirmed COVID-19 (e.g., in a waiting
room) or having spent time in the same airspace (e.g.,
the same examination room) for 0–2 hours after the
confirmed COVID-19 patient.
Not reported Within 6 feet for at least 10
minutes
Calvani 2021 Not defined Not reported Not reported
Canova 2020 Not defined Not reported 5 HCWs: >30 minutes
5 HCWs: >15-30 mins
6 HCWs: 5-15 mins
5 HCWs: ≤5 mins
Carazo 2021 Not defined Not reported Not reported
Cariani 2020 Not defined Not reported Not reported
Carvalho 2022 Not defined Not reported Not reported
Cerami 2021 Not defined Not reported Not reported
Charlotte 2020 Not defined Not reported 2-hours
Chaw 2020 Close contact: Any person living in the same
household as a confirmed case-patient or someone
who had been within 1 m of a confirmed case-patient
in an enclosed space for >15 minutes
Not reported Within 1m for >15 mins
Chen 2020 Close contact: All passengers were regarded as close
contacts
Not reported Flight duration 5 hours approx
Chen 2020a Close contacts are persons who have had close
contact with re-positive patients without effective
protection with masks, such as living and working
together
Not reported Not specified
Chen 2020b Not defined Not reported Not specified
Chen 2020c Community contact: Any close contact (being within
6 feet of the case-patient) for a prolonged time (>10
minutes); being an office co-worker of the case-
patient with close contact of any duration; contact
with infectious secretions from the case-patient; or
sharing a healthcare waiting room or area during the
same time and up to 2 hours after the case-patient was
present.
Healthcare contact: Face-to-face interaction between
healthcare personnel (HCP) and the case-patient without
wearing the full PPE that was recommended at the time
of the investigation or potential contact with the case-
patient’s secretions by HCP without wearing full PPE.
>10 mins to 2 hours
Cheng 2020 Not defined Not reported Not reported
Chu 2020 Close contact was a person who did not wear
appropriate PPE while having face-to-face contact
with a confirmed case for more than 15 minutes
during the investigation period. A contact was listed
as a household contact if he or she lived in the same
household with the index case. Those listed as family
contacts were family members not living in the same
household.
For health care settings, medical staff, hospital workers,
and other patients in the same setting were included;
close contact was defined by contacting an index case
within 2 m without appropriate PPE and without a
minimal requirement of exposure time
Those listed as family contacts were family members not
living in the same household.
Within 2 m without PPE, face-to-
face contact for >15 minutes
Chu 2021 Not defined Not reported Stayed ≥1 night in the household
during case’s infectious period
Contejean 2020 Close contact: Distance <2 meters for >10 minutes
was defined as close contact
Not reported <2 metres for >10 minutes
Cordery 2021 Not defined Pupil contacts were children who were either in the same
bubble as the Case (Bubble Contact, BC) or in a class within
the same school that was adjacent in terms of age-group
or proximity (School Contact, SC).
Household contacts (HC) were adults and children of any
age normally resident with the Case
Not reported
COVID-19 National
Emergency
Response Center
2020
Close contact (or high risk exposure)” was being within
2 meters of a COVID-19 case
Daily contact (or low risk exposure) was defined as having
proximity with a person who was a confirmed COVID-19
case, without having had close contact.
Not reported
Craxford 2021 Not defined Not reported Not reported
Danis 2020 All children and teachers who were in the same class
as the symptomatic pediatric case were considered as
high risk contacts and were isolated at home.
Moderate/high risk: Person who had prolonged
(> 15 min) direct face-to-face contact within 1 m with
a confirmed case, shared the same hospital room,
lived in the same household or shared any leisure or
professional activity in close proximity with a confirmed
case, or travelled together with a COVID-19 case in
any kind of conveyance, without appropriate individual
protection equipment.
Low risk: Person who had a close (within 1 m) but short
(< 15 min) contact with a confirmed case, or a distant (> 1 m)
but prolonged contact in public settings, or any contact in
private settings that does not match with the moderate/
high risk of exposure criteria.
Negligible risk: Person who had short (< 15 min)
contact with a confirmed case in public settings such as in
public transportation, restaurants and shops; healthcare
personnel who treated a confirmed case while wearing
appropriate PPE without any breach identified.
4 days in chalet
Dattner 2020 Not defined Not reported Not reported
de Brito 2020 Close contact: Close and prolonged contact in the
same room
Not reported Not specified
Deng 2020 Not defined Not reported Not reported
Desmet 2020 Not defined Not reported Not reported
Dimcheff 2020 Close contact: Within 2 m or 6 feet) with an individual
with confirmed COVID-19 for >15 minutes with the
example being exposed to a family member at home
who has had a positive COVID-19 nasal swab
Not reported Within 2m for >15 mins
Dong 2020 Not defined Not reported Not reported
Doung-ngern 2020 High-risk if they were family members or lived in the
same household as a COVID-19 patient, if they were
within a 1-meter distance of a COVID-19 patient longer
than 15 minutes; if they were exposed to coughs,
sneezes, or secretions of a COVID-19 patient and were
not wearing protective gear, such as a mask; or if they
were in the same closed environment within a 1-meter
distance of a COVID-19 patient longer than 15 minutes
and were not wearing protective gear
Not reported <15 min vs >15 min, <1m vs >1m
Draper 2020 Close contact was defined as anyone who had face-
to-face contact with a confirmed COVID-19 case for
more than 15 minutes cumulatively or continuously
(e.g., household setting or healthcare setting without
appropriate use of personal protective equipment)
or who was in the same room with an infectious case
for more than 2 hours (e.g., school room, workplace)
while a case was symptomatic or during the 24 hours
preceding symptom onset. Aircraft close contacts
included passengers seated in the same row as, or in
the two rows in front of or behind, an infectious case.
If the case was a crew member, the passengers in the
area in which the crew member worked were classified
as close contacts. Passengers disembarking from
cruise ships with high incidence of COVID-19 were also
classified as close contacts for surveillance purposes.
Not reported Not reported
Dub 2020 Close household contact, i.e., an individual sharing
the main residence of the secondary case
A regular household contact, i.e., an individual who would
regularly host or stay in the same residence of a secondary
case (stepsibling, divorced parent and new partner).
Extended contact, i.e., an individual who would have
frequent contact with the secondary case around and
after the exposure, for example, grandparents who were
involved in caring of the secondary case, according to
parents’ reports.
<2 meters for >10 minutes
Expert Taskforce 2020 Close contact: Cabinmates of confirmed case-patients Not reported Not specified
Farronato 2021 Not defined Not reported Not reported
Fateh-Moghadam 2020 Contact of a COVID-19 case has been considered any
person who has had contact with a COVID-19 case
within a time frame ranging from 48 hours before the
onset of symptoms of the case to 14 days after the
onset of symptoms
Not reported Not reported
Firestone 2020 Close contact: Being within 6 feet of a patient with
laboratory-confirmed COVID-19 infection for ≥15
minutes
Not reported Within 2m for >15 mins
Fontanet 2021 Not defined Not reported Not reported
Galow 2021 Not defined Not reported Not reported
Gamboa Moreno 2021 Not defined School contact was a close contact that originated from an
exposure to a case within the school environment.
Family or social contact was a contact with a case outside
the school environment.
Not reported
Gan 2020 Not defined Not reported Not reported
Gaskell 2021 Not defined Not reported Not reported
Ge 2021 A close nonhousehold contact was defined as an
individual exposed (within 1 meter) to an index patient
A household contact was defined as an individual in the
same household or an individual who dined together with
the index patient.
Within 1m
Ghinai 2020 Not defined Not reported Not reported
Gold 2021 Persons exposed to an index patient at school within
6 ft for >15 minutes per day during a 24-hour period
while the index patient was infectious (48 hours before
to 10 days after symptom onset or, if asymptomatic, 48
hours before to 10 days after specimen collection).
N/A <1m for >15 min
Gomaa 2021 Not defined Not reported Not reported
Gonçalves 2021 Not defined Not reported Not reported
Gong 2020 Close contact: Anyone who was closely in contact with
a suspected, confirmed and asymptomatic case without
effective personal protection (classified protection
according to the contact situation, including gloves,
medical protective masks, protective face screens,
isolation clothing, etc.) since onset of symptoms in
the suspected case and confirmed case or the day
asymptomatic case’s specimens were collected. The
close contact included: (i) living, working, or studying
in one house or classroom, (ii) diagnosing, treating,
or visiting cases in hospital ward, (iii) being within
short distance in the same vehicle, (iv) other situations
assessed by the field investigators.
Not reported Not reported
Gu 2020 Not defined Not reported 5 hrs, no natural ventilation or
face masks; distance between
each other <0.5 m
Hamner 2020 Close contact: Within 6 feet of infected case Not reported 2.5 hrs within 2 m
Han 2020 Close contact: Travel was defined as someone who
was in close contact with a confirmed case for over
three hours as they travelled to another region aside
from Region A. Close contact: meal was defined as
someone who was in close contact with a confirmed
case for over 30 minutes after having a meal together.
A casual contact was defined as someone who spent
several minutes with a confirmed case within the same
space without any mask on (or a person was established as
a contact by an Epidemic intelligence Officer).
30 mins to 3 hours
Hast 2022 Not defined Not reported Not reported
Heavey 2020 Close contact: Any individual who has had greater
than 15 minutes face-to-face (<2 meters distance*)
contact with a case, in any setting.
Casual contact: Any individual who has shared a closed
space with a case for less than two hours.
Up to 2 hours in duration
Helsingen 2020 Not defined Not reported Not reported
Hendrix 2020 Not defined Not reported Not reported
Hirschman 2020 Close contact: Within 6 feet of an infected person for
at least 15 minutes starting from 2 days before illness
onset.
Not reported "Hours"
Hobbs 2020 Close contact: Within 6 feet for ≥15 minutes) with a person with
known COVID-19, school or childcare
attendance, and family or community exposures ≤14
days before the SARS-CoV-2 test
Not reported Within 2 m for ≥15 minutes
Hoehl 2021 Not defined Not reported Not reported
Hong 2020 Anyone who ever came within 2 m of a diagnosed
patient without the use of effective personal protective
equipment
Not reported 258 person-days
Hsu 2021 Not defined Not reported Not reported
Hu 2020 A person who had co-travelled on a train within a three-
row seat distance of a confirmed case (index patient)
within 14 days before symptom onset.
Not reported Not reported
Hu 2021 Close contacts were defined as individuals who had
close-proximity interactions (within 1 meter) with
clinically suspected and laboratory-confirmed SARS-
CoV-2 cases, for the period from 2 days before, to 14
days after, the potential infector’s symptom onset. For
those exposed to asymptomatic subjects, the contact
period was from 2 days before, to 14 days after, a
respiratory sample was taken for real-time RT-PCR
testing. Close contacts included, but were not limited
to, household contacts (i.e., household members
regularly living with the case), relatives (i.e., family
members who had close contacts with the case but
did not live with the case), social contacts (i.e., a work
colleague or classmate), and other close contacts (i.e.,
caregivers and patients in the same ward, persons
sharing a vehicle, and those providing a service in
public places, such as restaurants or movie theatres)
Not reported Not reported
Hu 2021 Passengers within 3 rows of the index case seat were
considered to be close contacts for estimating the
upper bound of risk detailed below
Lower bound of risk: passengers assumed to be travelling
with their family members or friends if a small group of
passengers included one index COVID-19 patient, and
passengers seated immediately adjacent to this index
patient shared the same departure and destination.
Within 3 rows of the index case seat
Hua 2020 Not defined Not reported
Huang 2020 Close contacts quarantined at home or hospital Not reported Not reported
Huang 2020a Not defined Not reported Not reported
Huang 2021 Contact with the index case within 2 m without using
appropriate personal protective equipment (PPE) and
without a minimum requirement of exposure time in
hospital settings.
Not reported Not reported
Islam 2020 Close contact was defined as individuals who were
closely linked by contact tracing and were considered
a close contact group provided that no PPE was worn
having direct face to face contacts.
Household contacts were defined as individuals who lived
and were sharing the same room and same apartment in
the same household. Family contacts were those who are
the members of the same family but not living in the same
household.
Face-to-face
Jashaninejad 2021 Person who had exposure or lived with a probable or
confirmed case or had direct and face-to-face contact 2
days before and 14 days after exposure with the index
case.
Not reported Not reported
Jeewandara 2021 Close contacts were defined as individuals living in
Bandaranayaka watta and who had direct physical
contact or associated with cases (distance of 1m) within
a period of 2 days from identification of the index case.
Non-close contacts were defined as those who were living
within the CMC region as the cases, or those who worked
with cases in the same causal occupations but were not
qualified to be defined as close contacts.
Within 1m
Jia 2020 A close contact was defined as a person who did
not take effective protection against a suspected or
confirmed case 2 d before the onset of symptoms or
an asymptomatic infected person 2 d before sampling.
Not reported Not reported
Jiang 2020 Close contacts: Lived with the patients and individuals
who had contact with the patients within 1 meter
without wearing proper personal protection. Ct
value ≥40 was considered negative. The maximum
likelihood phylogenetic tree of the complete genomes
was conducted by using RAxML software with 1000
bootstrap replicates, employing the general time-
reversible nucleotide substitution mode
Not reported 1 m
Jing 2020 A close contact was defined as an individual who
had unprotected close contact (within 1 m) with a
confirmed case within 2 days before their symptom
onset or sample collection. Individuals who were linked
by contact tracing were considered a close contact
group
Not reported Not reported
Jing 2020a Not defined Not reported Not reported
Jones 2021 Close contacts were defined by analysis of video
footage for player interactions and microtechnology
(GPS) data for proximity analysis.
Not reported Within 1 m, face-to-face for ≥3
secs
Jordan 2022 Not defined Not reported Not reported
Kang 2020 Not defined Not reported Not reported
Kant 2020 Not defined Not reported Not reported
Karumanagoundar 2021 High-risk contact is defined as any person who was in
proximity with individuals positive for COVID-19 within
2 m of proximity for 15 min.
Contact: any individual comes in proximity with individuals
positive for COVID-19.
Low-risk contact is defined as any person who was in
proximity with individuals positive for COVID-19 and
sharing same environment but not having high exposure.
Household contact: any individual living in the same
household and comes in proximity with the individual with
COVID-19 confirmed.
Community contact: any individual other than living in the
same household and comes in proximity with the individual
with COVID-19 confirmed.
Congregation exposure: individual who have attended the
religious congregation event held during February and
March 2020 (newspaper reference)
<2m for >15min
Katlama 2022 Not defined Not reported Not reported
Kawasuji 2020 Not defined Not reported Not reported
Khanh 2020 Close contact: <2 m distance for >15 minutes.
Successfully traced passengers and crew members
were interviewed by use of a standard questionnaire,
tested for SARS-CoV-2
Not reported <2 m distance for >15 minutes.
Kim 2020 Not defined Household contact: Occurring at least 1 day after but
within 14 days from the last point of exposure.
2 days during the
presymptomatic period and 1
day during the symptomatic
period of the index case.
Kim 2020a Not defined Not reported 2 hrs to 4 days
Kim 2020b Contact was defined as presence in the same room
with COVID-19 confirmed patients, or in the same
outpatient clinic or examination room, 30 minutes
before and after COVID-19 confirmed patients. Within 2
m of confirmed patients (via CCTV)
Not reported Within 2 m of confirmed patients
for 30 mins
Kim 2021 Not defined Not reported Face-to-face
Kitahara 2022 Contact with confirmed case for >15 mins without
wearing proper PPE
Not reported >15 mins
Klompas 2021 Shared a room with an infected patient, and employees
who had face-to-face contact within 6 feet of an
infected employee or patient for at least 15 minutes
during which either party was not wearing a mask
Direct contact: spending ≥15 minutes interacting with staff
or patients on cluster units
<1m for >15 min
Kolodziej 2022 Not defined Not reported Not reported
Koureas 2021 Any person who had unprotected close contact (<2 m,
more than 15 min) with a confirmed case from 2 days
before symptom onset (if not available from sample
collection) until the patient’s isolation.
Household Secondary Contact: Any person residing in the
same house/apartment with a Household Index Case.
<2m for >15min
Kumar 2021 Not defined Not reported Not reported
Kuwelker 2021 Not defined Household members were defined as individuals who resided in the
same household as the index case.
Not reported
Kuwelker 2021 Not defined Household members were defined as individuals who
resided in the same household as an index patient.
Not reported
Kwok 2020 Close contacts referred to anyone who: (i) provided
care to the case (including a family member or
healthcare worker) or had other close physical contact;
or (ii) stayed at the same place (including household
members or visitors) while the case was ill.
Not reported Not reported
Ladhani 2020 Not defined Not reported Not reported
Ladhani 2020a Not defined Not reported Not reported
Laws 2020 Not defined Not reported Unclear
Laws 2021 Not defined Not reported Not reported
Laxminarayan 2020 High-risk contacts had close social contact or direct
physical contact with index cases without protective
measures
High-risk travel exposures—defined as close proximity
to an infected individual in a shared conveyance for ≥6
hours
Low-risk contacts were in the proximity of index cases but
did not meet criteria for high-risk exposure
Not reported
Lee 2020 Not defined: Frequent close contact Not reported >1 m
Lee 2020a Close contact (household contact) Not reported Mean contact period was
calculated to be 7.7 days.
Lewis 2020 Not defined Household contacts were defined as all persons living in
the same household as the primary patient.
Not reported
Li 2020 Not defined Not reported Unclear
Li 2020a Not defined Not reported Not reported
Li 2020b Close contact was defined as an act of sharing a meal,
party, vehicle or living room with a confirmed or latently
infected patient within 14 days.
Not reported Not reported
Li 2020c Close contacts were mainly those who have not
taken effective protection from close contact with
the suspected and confirmed cases 2 days before
symptoms appeared, or the asymptomatic infected
persons 2 days before the specimen collection.
Not reported Not reported
Li 2020d Not defined Not reported Not reported
Li 2021a Not defined Household contact of an identified case was broadly
defined as a family member or close relative who had
unprotected contact with the case within 2 days before the
symptom onset or test-positive specimen collection of the
case but did not necessarily live at the same address.
Not reported
Li 2021b Someone who had contact with an index case-patient
without effective protection and within 1 meter,
regardless of contact duration.
Persons who had close contact with the index case-
patient during or 2 days before the index case patient’s
illness onset were counted as close contacts
Not reported Within 1m regardless of duration
Lin 2021 Those in proximity to cases within 2 days before the
onset of symptoms of suspected and confirmed
cases or 2 days before the sampling of asymptomatic
infected persons when effective protection or
distancing measures were not in effect.
Close contacts also included those in proximity to
cases in aggregated epidemic settings within 2 weeks
before diagnosis such as homes, offices, school classes,
and so forth with 2 or more cases of fever and/or
respiratory symptoms.
Not reported Not reported
Liu 2020 Not defined Not reported Unclear
Liu 2020a Direct contact with patients with neo-coronary
pneumonia (within 1 m)
Not reported Within 1m for 2.5 hrs
Liu 2020b Close contacts were defined by the China Prevention
and Control Scheme of COVID-19.
Not reported 7.8 (95%CI: 7.0–8.7) close contacts per index case.
Liu 2020c Not defined Not reported Not reported
Liu 2021 Not defined Household contacts were broadly defined as any individual
residing with the index case during the infectious period.
Not reported
López 2020 Close contact: Anyone who was within 6 feet of a
person with COVID-19 for at least 15 minutes ≤2 days
before the patient’s symptom onset.
Not reported ≤1.83m of a person with COVID-
19 for at least 15 minutes
≤2 days before the patient’s
symptom onset
López 2021 Not defined Not reported Not reported
Lopez Bernal 2020 Household contacts were defined as those living or
spending significant time in the same household.
Household contacts, others with direct face to face
contact and healthcare workers who had not worn
recommended PPE
Not reported Not reported
Lopez Bernal 2022 Not defined Household contacts were defined as those living or
spending substantial time (overnight) in the same
household.
Other contacts: not classified as close contacts
Community contacts:
Not reported
Lucey 2020 Close contact: HCW or patient who spent more than
15 minutes face-to-face within 2 metres of a confirmed
case or patients who shared a multi-bedded room with
a confirmed case for more than 2 hours.
Not reported Not reported
Luo 2020 The tour coach was with 49 seats was fully occupied
with all windows closed and the ventilation system on
during the 2.5-hour trip.
Not reported 1 to 4.5m; up to 2.5 hours on
a bus
Luo 2020a Close contacts: Anyone who has had contact, without
effective protection regardless of duration of exposure,
with 1 or more persons with suspected or confirmed
COVID-19 any time starting 2 days before onset of
symptoms in persons with a suspected or confirmed
case, or 2 days before sampling for laboratory testing
of asymptomatic infected persons.
Not reported Not reported
Lyngse 2020 Not defined Not reported Not reported
Ma 2020 Not defined Not reported Longest contact time: 8 days
Shortest contact time: 0 days
Macartney 2020 Close contacts: Children or staff with face-to-face
contact for at least 15 min, or who shared a closed
indoor space for at least 40 min with a case during
their infectious period.
Not reported Face-to-face contact for at least
15 min, or who shared a closed
indoor space for at least 40 min
Malheiro 2020 Close contacts (high risk)were defined as individuals
who have spent 15 min or more in closeproximity (2 m
or less) to, or in a closed space with, a case.
Not reported Not reported
Maltezou 2020 Close contact was defined as a contact of >15 minutes
within a distance of <2 m with a COVID-19 case.
Household members were defined as persons living in the
same residence.
>15 minutes within <2 m
Maltezou 2020a Close contact was defined as a contact of >15 minutes
within a distance of <2 meters with a COVID-19 case
Household contacts were defined as persons either living
in the same residence or having close contacts with a
family member for >4 hours daily in the family residence.
Household: >4 hours daily
Close contact: >15 minutes
within <2 m
Mao 2020 Not defined Not reported Not reported
Martínez-Baz 2022 Any person who had face-to-face contact with a
confirmed COVID-19 infected individuals within 2 m
for more than a total of 15 minutes without personal
protection within a timeframe ranging from two days
before to 10 days after the onset of symptoms in
the case, or in the two days before 10 days after the
sample which led to confirmation was taken from
asymptomatic cases
Not reported Within 2m for >15 mins
Martinez-Fierro 2020 Individual who has had closer than <6 feet for ≥15 min
with people with a positive diagnosis for COVID-19
, whether they were symptomatic or asymptomatic
according to the CDC definition
Not reported ≥15 min at a distance of <1.83m
McLean 2022 Not defined Not reported Not reported
Mercado-Reyes 2022 Not defined Not reported Not reported
Metlay 2021 Not defined Not reported Not reported
Meylan 2021 Not defined Not reported Not reported
Miller 2021 Not defined Not reported Not reported
Montecucco 2021 A person who had exposure or lived with a probable or
confirmed case or had direct and face-to-face contact
exposure with the index case in the period between
two days before the positive PCR test or two days
preceding the onset of COVID-19 symptoms and end of
isolation after infection resolution.
Not reported Not reported
Mponponsuo 2020 An interaction of >15 minutes at a distance of <1 m Not reported >15 minutes at a distance of <1 m
Musa 2021 Not defined A household contact was defined as any person living
in the same household as the index case at the time of
recruitment.
Not reported
Ng 2020 Close contacts were individuals who had contact for
at least 30 min within a 2 m distance from the index
case.
Work contacts were defined as individuals who came
into close contact with the index case at work, from 2 days
before the onset of symptoms to isolation of the case, to
account for pre-symptomatic transmission.
Social contacts were defined as individuals who came
into close contact with the index case, from 2 days before
onset of symptoms to isolation of the case, through social
activities. Transport contacts were excluded
Lower risk contacts: Other contacts who were with the
index case for 10–30 min within 2 m
At least 30 min within a 2 m
Ng 2021 Not defined Household contact was defined as all persons living in
the same household of the index patient at diagnosis,
regardless of duration or proximity of contact.
Not reported
Ning 2020 Not defined Not reported Unclear
Njuguna 2020 Not defined Not reported Unclear
Nsekuye 2021 High risk contacts (red-ring) were those who had come
into unprotected face-to-face contact (within 2 m) or
having been in a closed environment (e.g., household
members) with a COVID-19 case for >15 min.
Unprotected direct contact with infectious secretions
of a COVID-19 case was also considered high risk
(red-ring: these are immediate family, friends, relatives
or co-workers that were more likely to have received
exposure to transmission).
A contact of a COVID-19 case was defined as any person
who had contact with a COVID-19 case within a timeframe
ranging from 72 h before the onset of symptoms of the
case to 14 days after the onset of symptoms.
Low risk contacts were those who had come into contact
while masked, within more than 2 m or for less than 15
min.
<2m for >15min
Ogata 2021 Not defined Not reported Not reported
Ogawa 2020 Not defined Not reported Not reported
Paireau 2022 Not defined Not reported Not reported
Pang 2022 Not defined Not reported Not reported
Park 2020 Not defined Not reported Not reported
Park 2020a High-risk contact (household contacts of COVID-19
patients, healthcare personnel)
Household contact was a person who lived in the
household of a COVID-19 patient and a nonhousehold
contact was a person who did not reside in the same
household as a confirmed COVID-19 patient.
Not reported
Park 2020b Not defined Not reported Not reported
Passarelli 2020 Not defined Not reported Not reported
Patel 2020 Not defined Not reported Not reported
Pavli 2020 Close contacts were defined as persons sitting within
a distance of <2 m for >15 min, including passengers
seated two seats around the index case and all crew
members and persons who had close contact with the
index case.
Not reported <2 m for >15 min
Petersen 2021 Household members and contacts who were within 2
meters of an infected person for >15 minutes, who had
direct physical contact or provided caregiving without
using personal protective equipment, or who had
similar exposures, were defined as close contacts.
Not reported <2m for >15min
Pett 2021 Not defined Household contact: living or spending significant time in
the same household.
High risk: persons in healthcare settings (e.g., healthcare
workers, cleaners, visitors) who have not worn
recommended PPE
OR laboratory workers who have not used appropriate
laboratory precautions during the following exposures to
the patient. OR
Direct contact with the case or their body fluids or their
laboratory specimens OR presence in the same room of a
healthcare setting when an aerosol generating procedure
is undertaken on the case

Lower risk: Persons in healthcare settings (e.g., healthcare
workers, cleaners) who have worn recommended PPE
during exposures to the patient.
Not reported
Phiriyasart 2020 Close contact was defined as a person who had at
least one of these following criteria : (i) a person who
came into close (within 1 meter) contact with, or had a
conversation with any patient for >5 minutes, or was
coughed or sneezed on by any patient when he/she did
not wear appropriate personal protective equipment
(PPE), e.g. a face mask, (ii) a person who was in an
enclosed space without proper ventilation, e.g. in the
same air-conditioned bus/air-conditioned room as any
patient , and was within one meter of any patient for
>15 minutes without wearing appropriate PPE.

High-risk close contact was defined as a close contact
who was likely to contract the virus from any patient
through exposure to respiratory secretions of any
patient while not wearing PPE according to standard
precautions.
A low-risk close contact was defined as a close contact who
was less likely to contract the virus from any patient. This
includes close contacts who have not met the definition for
high-risk close contacts.
Not reported
Poletti 2020 Not defined Not reported Not reported
Powell 2022 Not defined Direct contacts are defined as the staff and students who
were asked to self-isolate.
Indirect contacts refer to household members of these
staff and students.
Not reported
Pung 2020 Close contacts: People who spend a prolonged time
within 2 m of a confirmed case
Other contacts: People who had some interactions with
the case.
Unclear
Pung 2020a Close household contacts Not reported Unclear
Qian 2020 Four categories of infected individuals were considered
based on their relationship: family members, family
relatives, socially connected individuals, and socially
non-connected individuals
Not reported Not reported
Ratovoson 2022 Defined as those who lived in the same house of a
symptomatic index case up to 4 days before symptom
onset or of an asymptomatic index case up to 4 days
prior to the collection date of the first positive test
result.
Not reported
Ravindran 2020 Close contact: Face-to-face contact for greater than
15 minutes cumulative in the period extending from
48 hours before onset of symptoms in a confirmed
case; or sharing of closed space with a confirmed
case for a prolonged period of time in the period
extending from 48 hours before onset of symptoms in
a confirmed case.
Not reported Face-to-face contact for at least
15 min, or who shared a closed
indoor space for prolonged
period 48 hrs before onset of
symptoms
Razvi 2020 Not defined Not reported Not reported
Reukers 2021 Not defined Not reported Not reported
Robles Pellitero 2021 Not defined Not reported Not reported
Rosenberg 2020 Not defined Not reported
Roxby 2020 Not defined Not reported Not reported
Sakamoto 2022 Not defined Not reported Not reported
Sang 2020 Not defined Not reported Not reported
Sarti 2021 Not defined Not reported Not reported
Satter 2022 Not defined A contact was defined as an individual who experienced
any of the following exposures during the 2 days before
and the 14 days after the onset of symptoms of a
laboratory-confirmed COVID-19 case: (1) face-to-face
contact with a confirmed case within 1 m and for more
than 15 min (including travel, gossips, tea stall) or (2) direct
physical contact with a confirmed COVID-19 case.
<1m for >15 min
Schoeps 2021 A category-I contact is defined as a person who either
stayed face-to-face (<1·5 meters) with a COVID-19-case
for 15 minutes or longer, or in the same room
(i.e., irrespective of distance) for 30 minutes or longer
Not reported <1.5m for >15 min
Schumacher 2021 Close contact: Approximately 30–90 seconds in close
proximity (<1.5 m) of other players
Close social contacts (including sharing a car) 30–90 seconds in close proximity
(<1.5 m)
Schwierzeck 2020 Not defined Not reported Not reported
Semakula 2021 Not defined A contact of a COVID-19 case was defined as any person
who had contact with a COVID-19 case within a timeframe
ranging from 72 hours before the onset of
symptoms of the case to 14 days after the onset of symptoms
Not reported
Shah 2020 Household contact was defined as contact sharing
same residential address.
Not reported Not reported
Shah 2021 Not defined Household contact was defined as an individual sharing
shame postal address, and secondary case was defined
as individual developing infection within 14 days from last
contact with the index case.
Not reported
Shen 2020 Close contacts defined as individuals who had close,
prolonged, and repeated interactions with the 2 source
cases (Cases 2 and 3).
All other contacts are defined as casual contacts. Not reported
Sikkema 2020 Not defined Not reported Not reported
Son 2020 Not defined A contact was defined as anyone who was in contact with a
confirmed case from a day before the symptoms occurred,
in a manner that offered the potential for transmission
through respiratory droplets
Not reported
Song 2020 Shared the same bedroom, had dinner together Not reported Not reported
Sordo 2022 Not defined Close contacts were considered to be part of the same
household if they had the same address as the case.
Not reported
Soriano-Arandes 2021 Not defined Household contacts were defined as all persons living
in the same household as the first patient diagnosed,
regardless of the duration or proximity of the contact
Not reported
Speake 2020 2 rows in front and behind infectious passenger on an
airplane
Not reported Unclear
Stein-Zamir 2020 Not defined Not reported Not reported
Stich 2021 Not defined Not reported Not reported
Sugano 2020 Not defined Not reported Unclear
Sun 2020 Not defined Not reported Not reported
Sun 2021 Not defined Not reported Not reported
Sundar 2021 Not defined Contacts were those who were exposed to the index case
in the pre-symptomatic (2 days prior to symptom onset)
or symptomatic period and satisfied at least one of the
following: a) persons at residence of index case, b) persons
at workplace who were exposed to the index case at close
range (less than 6 feet) for ≥15 minutes, and c) persons
outside the index case residence or workplace with close
range contact ≥15 minutes who are traceable
<1m for >15 min
Tadesse 2021 Not defined Not reported Not reported
Tanaka 2021 Not defined Not reported Not reported
Tanaka 2022 Not defined Not reported Not reported
Taylor 2020 Not defined Not reported Unclear
Teherani 2020 Household contacts (HCs) were defined as an adult
(18 years) or a child (<18 years) who resided in the
home with the SIC at the time of diagnosis.
Not reported Not reported
Thangaraj 2020 Not defined Not reported Unclear
Torres 2020 Not defined Not reported Unclear
Tsang 2022 A close contact of a case is defined as any person
who was in close proximity to the case without any
personal protection equipment, starting 2 days before
the symptom onset of the case or specimen collection
if the case was asymptomatic. Close contact settings
include but are not limited to (1) living, working,
dining or taking classes with the case in the same
closed space or in proximity; (2) providing health care
to or visiting the case at a hospital; and (3) sharing
transportation with and in close proximity to the case
(in flights, passengers within 3 rows of seats in the front
and back of a case as well as crew members who had
been in proximity to a case were considered as close
contacts); and (4) other individuals in close proximity to
the cases as determined by field investigators.
Not reported Not reported
Tshokey 2020 Close friends, roommates, flight seat partner, spouse
or partner, cousin, physician, tour driver
Primary contacts: Individuals coming in some form of
contact with the confirmed cases such as conveyance in
the same cars/flights, encounter in clinics, serving meals,
or providing housekeeping services in hotels.
Secondary contacts: Individuals coming in contact with
the primary contacts
Unclear
Tsushita 2022 Not defined Not reported Not reported
van der Hoek 2020 Not defined Not reported
Vičar 2021 Not defined Not reported Not reported
Wang 2020 Not defined Not reported Unclear
Wang 2020a Not defined Not reported Unclear
Wang 2020b Close contact was defined as being within 1 m or 3 feet
of the primary case, such as eating around a table or
sitting together watching TV.
Not reported Unclear
Wee 2020 Not defined Not reported Within 2 m of the index case
for a cumulative time of ≥15
minutes, or who had performed
AGPs without appropriate PPE.
Wendt 2020 High-risk contacts: >15 min face-to-face contact,
sitting in a row behind physician for 45 mins, transfer in
an ambulance (45-min drive).
Not reported >15 min face-to-face contact
White 2022a A close contact was defined as an individual who was
within 1 m of a case of COVID-19 while wearing a mask,
or within 2 m if unmasked, in an indoor or outdoor
setting for a cumulative total of 15 min or more over a
24-hour period during the case’s infectious period.
Not reported <2m for >15 min
White 2022b A close contact was defined as an individual sitting
within a two-seat radius of an infectious case, where
one infectious case was identified on a flight. If any
close contact sitting within a two-seat radius of an
infectious case tested positive, all passengers on board
were then considered close contacts. If there were two
or more unrelated infectious cases on board the same
flight, all passengers were considered close contacts.
Not reported Within a two-seat radius of an
infectious case
Wiens 2021 Not defined Households were defined as a group of individuals that
sleep under the same roof most nights and share a
cooking pot.
Not reported
Wolf 2020 Not defined Not reported Not specified
Wong 2020 Contact case was defined as a patient or staff who
stayed or worked in the same ward as the index
patient. Patients who shared the same cubicle with the
index case were considered as ‘patient close contact’.
Staff close contact: Staff who had contact within 2 m
of the index case for a cumulative time of >15 min, or
had performed AGPs, without ‘appropriate’ PPE.
Casual contacts: All staff and patients who did not fulfil the
pre-defined criteria for close contacts.
Casual/low-risk contact: HCW wearing a facemask or
respirator only and have prolonged close contact with a
patient who was wearing a facemask, or HCW using all
recommended PPE or HCW (not using all recommended
PPE) who have brief interactions with a patient regardless
of whether patient was wearing a facemask.
Patient close contacts were quarantined into an AIIR (or
quarantine camp if the patient was deemed clinically stable
to be discharged from hospital) for 14 days.
Within 2 m of the index case for
a cumulative time of >15 min
Wood 2021 Not defined Not reported Not reported
Wu 2020 Close contact: Been within 1 metre of a confirmed
case, without effective PPE, within the period for 5 days
before the symptom onset in the index case or 5 days
before sampling if the index case was asymptomatic.
Not reported Within 1 metre of a confirmed case,
without effective PPE
Wu 2020a Household contacts were defined as person who spent
at least 1 night in the house after the symptom onset
of the index patient. A household was defined as ≥2
people living together in the same indoor living space.
A household index was the first person to introduce
SARS-CoV-2 into the household.
Not reported At least 1 night
Wu 2021 Close contacts of symptomatic cases were individuals
who had exposed to a confirmed patient of SARSCoV-2
infection without wearing proper PPE (including
practising optimal hand hygiene or wearing gloves, and
wearing surgical facemasks and gowns) and/or stayed
with the case in close proximity (<1m) in a close/
semi-close environment such as household, office,
elevator, etc., which should have occurred within two
days before the onset of the symptomatic case until
when the symptomatic index case was isolated.

Close contacts of asymptomatic SARS-CoV-2 infections
were people who had a close contact (same definition
as above) with the confirmed asymptomatic index case
within two days before the asymptomatic case provided
specimens to test for SARS-CoV2 to the time when the
index case was isolated.
Not reported <1m for >15 min
Xie 2020 Close contact: An individual who has not taken
effective protection when in proximity of suspected or
confirmed cases 2 days before the onset of symptoms
or 2 days before the collection of asymptomatic
specimens.
Not reported Unclear
Xie 2021 Not defined Not reported Not reported
Xin 2020 Close contacts were defined as persons who had a
short-range contact history for 2 days before the onset
of symptoms in COVID-19-suspected and -confirmed
cases, or 2 days before the collection of samples from
asymptomatic cases without taking effective protective
measures, such as family members in the same house,
direct caregivers, and medical staff who provided
direct medical care, colleagues in the same office or
workshop, etc.
The effective contact duration for the close contacts
was defined as the contact days with index patients with
confirmed COVID‐19, which was calculated as the last
contact date minus the start contact date, and all dates
were corresponding to the definition of close contacts
The median effective contact
duration with patients with
COVID‐19 was 4 (IQR: 1–6) days,
with 57 (53.8%) experiencing
effective contact between 3
and 11 days, and 9 (8.5%) with
effective contact duration
> 11 days
Yang 2020 Close contacts: Unprotected exposure. Candidate contacts: Teachers and classmates Not reported
Yau 2020 Close unprotected contact with someone who has
tested positive for COVID-19 in the last 14 days
Not reported Unclear
Ye 2020 Not defined Not reported Not reported
Yi 2021 Not defined Not reported Not reported
Yoon 2020 Close contact was defined as a person who had
face-to-face contact for >15 minutes or who had direct
physical contact with the index case-patient. Persons
who used the same shuttle bus were also considered
to be close contacts.
Not reported Face-to-face contact for
>15 minutes or direct physical
contact
Yousaf 2020 Not defined Not reported Not reported
Yu 2020 Close contacts were defined as those who lived in the
same household, shared meals, travelled or had social
interactions with a confirmed case two days before the
onset of COVID-19 symptoms
Not reported Not reported
Yung 2020 Not defined Not reported Not reported
Zhang 2020 Not defined Not reported Not reported
Zhang 2020a Close contact: Refers to a person who had contact
with index case without using proper protection during
2 days before the index case was tested.
Not reported Not reported
Zhang 2020b Not defined Not reported Not reported
Zhang 2020c Close contacts were individuals who lived with a PCR-
confirmed case or interacted with a case within 1 metre
from the case without any personal protections.
Not reported Within 1m of case
Zhang 2020d Not defined Not reported Not reported
Zhang 2021 Not defined Not reported Not reported
Zhuang 2020 Not defined Not reported Not reported