Table 1.
List of proteins known to undergo aggregation upon in vitro refolding from denaturant.
| Protein name | Number of residues) | Size of monomer (kDa) | Number of domains | Monomer or complex | Reference |
|---|---|---|---|---|---|
| Luciferase | 550 | 60 | 2 | monomer | [259] |
| Rhodanese | 293 | 33 | 2 | monomer | [324] |
| Rubisco | 474 (large subunit), 122 (small subunit) | 520 total, 50 for large subunit, 15 for small subunit | 1 | hexadecamer (8 small subunits, 8 large subunits) | [325] |
| Apomyoglobin | 153 | 17 | 1 | monomer | [326] |
| Galactitol-1-phosphate 5-dehydrogenase | 346 | 37.4 | 2 | tetramer | [109] |
| Glutamate decarboxylase alpha | 466 | 52.7 | 3 | hexamer | [109] |
| Threonyl-tRNA synthetase (ThrRS) | 642 | 74 | 4 | dimer | [109] |
| 5,10-methylenetetrahydrofolate reductase | 296 | 33.1 | 1 | tetramer | [109] |
| S-adenosylmethionine synthetase | 384 | 41.8 | 3 | tetramer | [109] |
| Dihydrodipicolinate synthase (DHDPS) | 292 | 31.3 | 2 | tetramer | [109] |
| Tagatose-1,6-bisphosphate aldolase gatY (TBPA) | 286 | 30.8 | 1 | monomer | [109] |
| Tryptophanase | 471 | 52.8 | 2 | tetramer | [327] |
| α1-antitrypsin | 418 | 44.4 | 1 | monomer | [328] |