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Recombinant human IL-12 stimulates proliferation of activated PBMCs from baboons compared to that observed in humans. IL-12 was added 72 h after PBMCs (5 × 104/ml) were activated with ConA (0.5 μg/ml in two baboons) or PHA (1 μg/ml in humans), and the mixtures were incubated an additional 18 h prior to addition of [3H]thymidine. Values are means ± SD of triplicate cultures.
