Table 2.
Clinical, laboratory, echocardiography and medication results in patients with ACS and T2D
| Variables | ACS (n = 34) | T2D (n = 34) | ACS and T2D (n = 36) |
|---|---|---|---|
| Clinical characteristics | |||
| BMI (kg/m2), mean ± SD | 25.46 ± 2.23 | 25.05 ± 3.00 | 25.71 ± 2.91 |
| DAC (cm), mean ± SD | 90.56 ± 10.11 | 91.71 ± 6.73 | 90.94 ± 8.55 |
| Heart rate (bpm), mean ± SD | 71.29 ± 12.36 | 75.00 ± 13.98 | 74.72 ± 11.81 |
| Systolic BP (mmHg), mean ± SD | 138.59 ± 22.40 | 147.41 ± 19.81 | 133.39 ± 23.72 |
| Diastolic BP (mmHg), mean ± SD | 77.12 ± 14.21 | 85.35 ± 10.03 | 76.56 ± 20.00 |
| Laboratory parameters | |||
| TnI (ng/mL), median (IQR 25%–75%) | 0.02 (0.00–0.27) | – | 0.23 (0.02–1.02) |
| TnT (ng/mL), median (IQR 25%–75%) | 0.01 (0.01–0.39) | – | 0.03 (0.01–0.12) |
| CK (U/L), median (IQR 25%–75%) | 141.00 (89.25–249.75) | – | 66.50 (56.00–123.00) |
| CK–MB (ng/mL), median (IQR 25%–75%) | 2.30 (1.25–6.78) | – | 1.80 (1.10–4.90) |
| LDH (U/L), median (IQR 25%–75%) | 194.00 (168.00–267.50) | – | 189.00 (153.00–222.00) |
| NT–proBNP (pg/mL), median (IQR 25%–75%) | 187.00 (83.40–656.25) | – | 524.00 (106.00–989.00) |
| Scr (μmol/L), mean ± SD | 64.81 ± 12.92 | 67.71 ± 16.95 | 68.93 ± 10.09 |
| HBA1c (%), median (IQR 25%–75%) | 6.00 (5.78–6.13) | 8.20 (6.55–9.88) | 7.60 (6.60–8.50) |
| FBG (mmol/L), median (IQR 25%–75%) | – | 7.20 (6.15–11.43) | 6.90 (6.00–11.40) |
| TC (mmol/L), mean ± SD | 4.71 ± 0.85 | 4.62 ± 1.27 | 3.38 ± 0.69 |
| TG (mmol/L), mean ± SD | 1.43 ± 0.54 | 1.34 ± 0.50 | 1.56 ± 0.65 |
| HDL (mmol/L), mean ± SD | 1.10 ± 0.24 | 1.27 ± 0.23 | 1.07 ± 0.46 |
| LDL (mmol/L), mean ± SD | 2.76 ± 0.65 | 2.57 ± 0.85 | 1.76 ± 0.52 |
| Sodium (mmol/L), mean ± SD | 139.48 ± 1.83 | 140.53 ± 2.87 | 140.64 ± 2.59 |
| Potassium (mmol/L), mean ± SD | 3.89 ± 0.41 | 4.16 ± 0.37 | 4.04 ± 0.37 |
| Echocardiography, mean ± SD | |||
| LVEF (%) | 62.91 ± 8.68 | – | 62.83 ± 8.12 |
| E/A | 0.78 ± 0.23 | – | 0.87 ± 0.22 |
| Cardiac index (L/min/m2) | 2.68 ± 0.53 | – | 2.89 ± 0.49 |
| Concomitant medication, n (%) | |||
| Statin | 30 (88) | 22 (65) | 30 (83) |
| Aspirin | 24 (71) | 18 (53) | 32 (89) |
| Clopidogrel/ticagrelor | 26 (76) | 2 (6) | 30 (83) |
| ACE inhibitor/ARB | 8 (24) | 10 (29) | 18 (50) |
| Beta blocker | 24 (71) | 10 (29) | 24 (67) |
| Calcium channel blocker | 14 (41) | 18 (53) | 12 (33) |
| Insulin | – | 16 (47) | 10 (28) |
| ICA stenosis degree, n (%) | |||
| No stenosis | 2 (6) | 10 (29) | 8 (22) |
| Mild | 20 (59) | 14 (41) | 6 (17) |
| Moderate | 8 (24) | 6 (18) | 8 (22) |
| Severe | 4 (12) | 4 (12) | 14 (39) |
BMI, body mass index; BP, blood pressure; TnI, troponin I; IQR, interquartile range; TnT, troponin T; CK, creatine kinase; CK-MB, creatine kinase isoenzyme-MB; LDH, lactate dehydrogenase; NT-proBNP, N-terminal pro-B-type natriuretic peptide; Scr, serum creatinine; HBA1c, hemoglobin A1c; FBG, fasting blood glucose; TC, total cholesterol; TG, triacylglycerol; HDL, high-density protein; LDL, low-density protein; LVEF, left-ventricular ejection fraction; E/A, ratio of early to late transmitral flow velocity; ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; ICA, internal carotid artery