Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 4;13:63. doi: 10.1186/s13293-022-00474-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 5 — Gonadal and chromosomal sex regulate fatty acid metabolism. A Heatmaps display relative hepatic expression levels of genes related to fatty acid synthesis and peroxisomal beta oxidation in Apoe^–/– FCG genotypes (N = 3). Expression of each genotype was relative to that in XX mice with ovaries. *P < 0.05 for gonadal or chromosomal sex by two-way ANOVA. Real-time PCR quantification of representative genes from A showing B chromosomal sex effects (Acsl1 and Acsl4), C gonadal sex effects (Scd2 and Phyh) and D both gonadal and chromosomal sex effects (Slc27a2). Two-way ANOVA with * donating gonadal sex effect and † denoting chromosomal sex effect. * or ^†P < 0.05 and ** or ^††P < 0.01. N = 4–6. In two-way ANOVA analyses, two groups of mice were combined such that the number of mice in each group used for statistical analysis is 7–12