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. 2022 Oct 24;119(44):e2209933119. doi: 10.1073/pnas.2209933119

Fig. 3.

Fig. 3.

Dominance in phase response upon different zeitgeber combinations. (A) PTC matrix of the response to Dex and PMA given in different concentrations. Each point represents the phases of a single cell. Data are double plotted for clarity. Pink: type 1 resetting model ± 95% confidence interval, green: type 0 resetting model ± 95% confidence interval, ns: P > 0.05 in bootstrapping test for response, n = 151 to 328 cells per concentration (SI Appendix, Dataset S3). (B) Type 1 PTC amplitude in each combination of Dex and PMA from (A). (C) Vector plot of the type 1 PTC phase (pink) and type 0 mean new phase (green) in each combination of Dex and PMA from (A). Vector direction represents the relative phase ± SD from bootstrapping-based distribution. (D) PTC matrix of the response to Dex and FK given in different concentrations. Each point represents the phases of a single cell. Data are double plotted for clarity. Pink: type 1 resetting model ± 95% confidence interval, green: type 0 resetting model ± 95% confidence interval, ns: P > 0.05 in bootstrapping test for response, n = 91 to 208 cells per concentration (SI Appendix, Dataset S4). (E) Vector plot of the type 1 PTC phase (pink) and type 0 mean new phase (green) in each combination of Dex and FK from (D). Vector direction represents the relative phase ± SD from bootstrapping-based distribution.