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Structural details at mutational hotspot-353. (A) Interface between the prototypic RBM and human VBMs. PDB ID: 6VW1. (B) Interface between the omicron RBM and human VBMs. (C) Interface between the omicron RBM and mouse VBMs. Dotted lines indicate salt bridges, hydrogen bonds, hydrogen-π interaction, or anion-π interaction. Double-ended red arrow indicates repulsion.
