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. 2022 Oct 29;2022:1668000. doi: 10.1155/2022/1668000

Figure 5.

Figure 5

The effect of AIF-1 or miR-34a on autophagy, inflammation, and ROS in HRGECs. (a, b) The effect of AIF-1 on the expression of miR-34a, ATG4B, LC3II, p62, and NLRP3 protein in HRGECs. Versus control group, ∗P < 0.001. (c, d) The effect of miR-34a on the expression of ATG4B, LC3II, p62, NLRP3, and ROS in HRGECs. All the relative levels of results were corrected by total protein. Versus control group, ∗P < 0.001. HRGECs: human renal glomerular endothelial cells; AIF-1: allograft inflammatory factor-1; miR-34a: microRNA 34a; ATG4B: autophagy related 4 homolog B; LC3II and p62: autophagy-associated protein; NLRP3: NOD-like receptor thermal protein domain associated protein 3; ROS: reactive oxygen species.