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. 2022 Nov 5;13(11):929. doi: 10.1038/s41419-022-05373-9

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Fig. 4 — There are complex connects among multiple PCD, and the relation of them are not fixed but flexible which depends on the physiological and pathological conditions. HSP90 regulates some key procedures of the PCD transformation, including the Beclin1/Bcl-2 complex, Beclin1/SLC7A11 complex, mitochondrial complex I and complex II.