FIG. 5.

Protection against P. yoelii malaria induced by immunization with recombinant antigens of pypAg-1. Groups of CByB6F1/J mice (n = 5) were immunized with liposome-encapsulated pAg-1N (•) or pAg-1C (⧫) along with Quil A as the adjuvant. Control animals (n = 5) were immunized with empty liposomes plus Quil A (□). Animals were given boosters twice at 3-week intervals and challenged with 10⁶ P. yoelii 17X-parasitized erythrocytes. Resulting parasitemias were monitored by enumerating parasitized erythrocytes in thin tail-blood smears stained with Giemsa stain.