FIG. 6.

Effect of an NF-κB-specific inhibitor on IL-8 production by human monocytes and PMN. Cells were incubated with CAPE (100 μM) for 1 h prior to LPS (1 μg/ml) or LAMPf (1 μg/ml) stimulation. DMSO (1%) was used as the solvent control. IL-8 production was measured by ELISA 18 h after stimulation and normalized to cells that received no treatment prior to stimulation. Data presented are means ± SEM of four and three distinct experiments for monocytes and PMN, respectively.