Table 1. Baseline patient demographics and characteristics.

Characteristic	Number of patients		%
Median age, years (range)		61 (22-86)
Males (n)	3		37.5
Females (n)	5		62.5
Race: white (n)	8		100
Diagnosis: dose escalation part
Refractory glioblastoma (n)	2		25
Amyotrophic lateral sclerosis (n)	1		12.5
Primary progressive aphasia/dementia (n)	1		12.5
Diagnosis: dose expansion part
Diabetes, type 1 (n)	1		12.5
Parkinson’s disease (n)	3		37.5