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Eighty‐two subjects of 454 had a low local von Willebrand factor (VWF) ristocetin cofactor activity (VWF:RCo), but normal local and central VWF antigen (VWF:Ag), normal VWF glycoprotein‐IbM activity (VWF GPIbM), which resulted in abnormal VWF:RCo/VWF:Ag vs. VWF:GPIbM ratio (p < 0.0001)
