TABLE 2.

The Mendelian randomization pleiotropy residual sum and outlier (MR-PRESSO) tests of the relationship between telomere length (TL) and cardiovascular diseases (CVDs).

Outcome	Raw estimates				Outlier corrected estimates
	N	OR	95% CI	P-value	N	OR	95% CI	P-value
Hypertension	130	1.12	1.02–1.23	0.02	–	–	–	–
Myocardial infarction	128	0.73	0.63–0.84	<0.01	–	–	–	–
Coronary atherosclerosis	128	0.85	0.76–0.95	<0.01	–	–	–	–
Ischemic heart disease	128	0.87	0.78–0.96	<0.01	127	0.86	0.78–0.94	<0.01
Heart failure	119	0.95	0.88–1.03	0.21	–	–	–	–
Atrial fibrillation	130	1.03	0.94–1.12	0.55	125	1.02	0.95–1.10	0.58
Stroke	116	0.88	0.80–0.95	<0.01	115	0.89	0.82–0.96	<0.01
Cardiac death	138	0.96	0.85–1.10	0.56	–	–	–	–

OR, odds ratio; CI, confidence interval.