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Schematic representation of the genomic organization of SARS-CoV-2. The SARS-CoV-2 genome, ~30 kilobases (Kb), encodes fifteen open reading frames (ORFs) for non-structural (dark grey: ORF1a and ORF1b), structural (light blue: spike (S), envelope (E), membrane (M) and nucleocapsid (N)), and accessory proteins (white: ORF3a, 3b, 6, 7a, 7b, 9a, 9b, and 10) with ORF8 shown in red. The accessory proteins (dashed box) are interspersed among or within the genes encoding structural proteins.
