Table 1.
Example search strategy on EMBase (via Ovid)
| No. | Searches | Results |
|---|---|---|
| 1 | Muscle atrophy/ | 36,116 |
| 2 | Sarcopenia/ | 10,943 |
| 3 | (sarcop?en* or osteosarcop?en*).ti,ab,kw | 14,877 |
| 4 | ("age-related musc*" or "ag?ing musc*" or "muscle wast*" or "muscle loss").ti,ab,kw | 10,775 |
| 5 | ("skeletal muscle*" or "muscle mass").ti,kw | 69,777 |
| 6 | Osteoporosis/ | 121,817 |
| 7 | Bone disease/ or bone erosion/ or bone fragility/ or demineralization/ or metabolic bone disease/ | 47,356 |
| 8 | Osteoarthritis/ | 93,622 |
| 9 | Rheumatoid arthritis/ | 201,956 |
| 10 | ("bone loss" or "ag?ing bone*" or "age-related bone*" or "bone mineral density" or BMD or "bone density").ti,ab | 112,175 |
| 11 | (sirolimus or everolimus or temsirolimus or ridaforolimus or deforolimus or zotarolimus).ti,ab | 29,364 |
| 12 | rapamycin.ti,kw | 11,712 |
| 13 | rapalog*.ti,ab,kw | 604 |
| 14 | 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 | 603,025 |
| 15 | 11 or 12 or 13 | 40,098 |
| 16 | 14 and 15 | 589 |
| 17 | Limit 16 to (article or article in press) | 333 |