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DNA-PKcs deletion sustains kidney function in the sepsis setting. (A-B) Serum levels of BUN and creatinine (Cr) were determined by ELISA in LPS-treated control and DNA-PKcsTKO mice. (C) Estimation of the tubular injury index through H&E staining. (D-F) Immunofluorescence analysis of IL-6 and TNFα expression in kidney tissues. (G-H) qPCR was applied to analyze the transcription of IL-6 and TNFα in renal samples. *p < 0.05.
