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. 2022 Jan 31;41:39–48. doi: 10.1016/j.jare.2022.01.014

Fig. 6.

Fig. 6

DNA-PKcs deletion preserves mitochondrial dynamics, biogenesis, and mitophagy in renal cells exposed to LPS. (A-C) Mitochondrial fragmentation was determined in control and DNA-PKcs-deficient HK2 cells through immunofluorescent labeling of TOM20. (D-G) qPCR was applied to analyze the transcription of Drp1, Mff, Mfn2, and Opa1 in HK2 cells. (H-I) Analysis of mitophagy in LPS-exposed HK2 cells using the mt-Kemia assay. (J-K) The transcription of Pgc1α and Tfam in HK2 cells was determined through qPCR. *p < 0.05.