Table 2.
Multivariate Analysis of Complete Response and Overall Survival
| Characteristic | Logistic Regression for CR | Cox Proportional Hazard for OS | ||||||
|---|---|---|---|---|---|---|---|---|
| No. | OR | 95% CI | P | No. | HR | 95% CI | P | |
| Vitamin D status | ||||||||
| > 30ng/mL | 38 | — | — | 38 | — | — | ||
| ≤ 30ng/mL | 73 | 2.58 | 1.05 to 6.83 | 0.045 | 73 | 2.24 | 1.08 to 4.66 | 0.030 |
| Age | ||||||||
| ≤ 65-years | 53 | — | — | 53 | — | — | ||
| > 65-years | 58 | 1.36 | 0.56 to 3.37 | 0.49 | 58 | 1.99 | 1.02 to 3.91 | 0.044 |
| Primary refractory disease | ||||||||
| No | 78 | — | — | 78 | — | — | ||
| Yes | 32 | 2.73 | 1.12 to 6.91 | 0.029 | 32 | 2.42 | 1.23 to 4.74 | 0.010 |
| CAR-T costimulatory domain | ||||||||
| 41BB | 51 | — | — | 51 | — | — | ||
| CD28 | 60 | 0.75 | 0.30 to 1.83 | 0.52 | 60 | 0.72 | 0.37 to 1.40 | 0.33 |
CR, complete response; OS overall survival; CAR-T, chimeric antigen receptor T-cell therapy