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. 2022 Aug 27;15(11):2112–2125. doi: 10.1002/aur.2808

TABLE 2.

Medical conditions by age group

All By age group p‐value
18–19 20–24 25–29 30–34 35–39 40+
(N = 4657) (N = 353) (N = 863) (N = 874) (N = 744) (N = 614) (N = 1209)
N % N % N % N % N % N % N %
Birth defects
Skeletal 91 2.0 6 1.7 10 1.2 18 2.1 10 1.3 16 2.6 31 2.6 0.15
Craniofacial 23 0.5 3 0.8 1 0.1 2 0.2 3 0.4 6 1.0 8 0.7 0.14
Involving CNS (spina bifda, brain malformation) 36 0.8 1 0.3 1 0.1 7 6 0.8 6 1.0 15 1.2 0.08
Thorax (heart and lung) 57 1.2 5 1.4 5 0.6 12 1.3 7 0.9 8 1.3 20 1.7 0.35
Gastrointestinal system 29 0.6 1 0.3 3 0.3 6 0.7 3 0.4 9 1.5 7 0.6 0.09
Urogenital 15 0.3 0 0.0 2 0.2 1 0.1 2 0.3 4 0.7 6 0.5 0.32
Any of the above 197 4.2 16 4.5 21 2.4 38 4.3 27 3.6 35 5.7 60 5.0 0.03
Birth or pregnancy complications
Premature births (delivery before 37 weeks) 334 7.2 26 7.4 59 6.8 75 8.6 61 8.2 40 6.5 73 6.0 0.25
Intraventricular hemorrhage 13 0.3 2 0.6 3 0.3 5 0.6 1 0.1 0 0.0 2 0.2 0.24
Insufficient O2 at birth with NICU stay 164 3.5 13 3.7 34 3.9 38 4.3 24 3.2 24 3.9 31 2.6 0.31
Any of the above 418 9.0 33 9.3 74 8.6 95 10.9 73 9.8 54 8.8 89 7.4 0.13
Cognitive functioning
Cognitive delays or impairment due to another medical condition or exposure (e.g., brain injury, stroke, lead poisoning, FAS, HIV, radiation, hydrocephalus, brain tumor, drug effects, etc.) 272 5.8 8 2.3 49 5.7 46 5.3 39 5.2 39 6.4 91 7.5 0.007
Intellectual disability, cognitive impairment, global developmental delay, or borderline intellectual functioning 283 6.1 26 7.4 67 7.8 67 7.7 47 6.3 33 5.4 43 3.6 <0.001
Any of the above 484 10.4 29 8.2 101 11.7 100 11.4 77 9.9 63 10.3 114 9.4 0.34
Developmental delays & disorders
Language delay or disorder 618 13.3 51 14.4 144 16.7 151 17.3 101 13.6 66 10.7 105 8.7 <0.001
Mutism 66 1.4 1 0.3 16 1.9 15 1.7 7 0.9 9 1.5 18 1.5 0.28
Speech articulation problems 562 12.1 50 14.2 115 13.3 121 13.8 97 13.0 63 10.3 116 9.6 0.011
Learning disability (LD, learning disorder, including reading, written expression, math, or NVLD [Nonverbal learning disability]) 973 20.9 69 19.5 212 24.6 205 23.5 178 23.9 131 21.3 178 14.7 <0.001
Motor delay (e.g., delay in walking) or developmental coordination disorder 306 6.6 27 7.6 71 8.2 76 8.7 42 5.6 38 6.2 52 4.3 <0.001
Any of the above 1410 30.3 107 30.3 314 36.4 317 36.3 233 31.3 175 28.5 264 21.8 <0.001
Sleep problems diagnosed by a professional
Sleep disorder or problem 1238 26.6 63 17.8 189 21.9 218 24.9 210 28.2 181 29.5 377 31.2 <0.001
Neurological conditions
Seizure disorder or epilepsy 299 6.4 16 4.5 60 7.0 71 8.1 46 6.2 44 7.2 62 5.1 0.057
Traumatic brain injury (hospitalized) 111 2.4 4 1.1 12 1.4 22 2.5 15 2.0 13 2.1 45 3.7 0.007
Brain infection such as bacterial meningitis, encephalitis 41 0.9 3 0.8 4 0.5 4 0.5 9 1.2 6 1.0 15 1.2 0.28
Lead poisoning 17 0.4 0 0.0 4 0.5 4 0.5 4 0.5 0 0.0 5 0.4 0.46
Other neurological conditions
No 4148 89.1 320 90.7 774 89.7 787 90.0 656 88.2 536 87.3 1075 88.9 0.45
Yes 509 10.9 33 9.3 89 10.3 87 10.0 88 11.8 78 12.7 134 11.1
Any of the above 843 18.1 48 13.6 150 17.4 166 19.0 142 19.1 125 20.4 212 17.5 0.13
Growth conditions
Short stature 107 2.3 7 2.0 16 1.9 26 3.0 18 2.4 18 2.9 22 1.8 0.41
Difficulty gaining weight 64 1.4 2 0.6 19 2.2 12 1.4 15 2.0 4 0.7 12 1.0 0.035
Obesity 372 8.0 14 4.0 57 6.6 89 10.2 70 9.4 50 8.1 92 7.6 0.003
Small head size (microcephaly) 20 0.4 1 0.3 4 0.5 1 0.1 4 0.5 6 1.0 4 0.3 0.22
Large head size (macrocephaly) 49 1.1 2 0.6 10 1.2 13 1.5 2 0.3 8 1.3 14 1.2 0.2
Other growth conditions
No 4558 97.9 345 97.7 845 97.9 853 97.6 728 97.8 601 97.9 1186 98.1 0.99
Yes 99 2.1 8 2.3 18 2.1 21 2.4 16 2.2 13 2.1 23 1.9
Any of the above 551 11.8 26 7.4 97 11.2 127 14.5 101 13.6 68 11.1 132 10.9 0.005
Vision or hearing conditions
Deafness/hearing loss 288 6.2 12 3.4 43 5.0 34 3.9 52 7.0 41 6.7 106 8.8 <0.001
Blindness 39 0.8 3 0.8 11 1.3 13 1.5 3 0.4 2 0.3 7 0.6 0.051
Cataract 82 1.8 2 0.6 8 0.9 5 0.6 8 1.1 5 0.8 54 4.5 <0.001
Strabismus 186 4.0 17 4.8 34 3.9 36 4.1 26 3.5 21 2.4 52 4.3 0.85
Any of the above 508 10.9 30 8.5 87 10.1 80 9.2 78 10.1 63 10.3 170 14.1 0.003