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. 2022 Oct 24;13:1002329. doi: 10.3389/fimmu.2022.1002329

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Copyright © 2022 Shimizu, Matsumoto, Sasajima, Suzuki, Okubo, Fujita, Temmoku, Yoshida, Asano, Ohira, Ejiri and Migita

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical imagings. (A) Chest non-contrast CT findings. Chest non-contrast CT revealed bilateral ground-glass opacity. (B) MRI findings of bilateral lower limbs. MRI shows high signals on STIR in the bilateral vastus lateralis, suggesting muscular inflammation. MRI, magnetic resonance imaging; STIR, short T1 inversion recovery. (C-E) The slide showed (C) inflammatory cell infiltration around the myofiber bundles, (D) perivascular inflammatory cell infiltration, and (E) CD8-positive lymphocytes infiltration in atrophy of the myofibers. CT, computed tomography; HE, hematoxylin-eosin; MRI, magnetic resonance imagin; STIR, short T1 inversion recovery; CD, cluster of differentiation.