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. 2022 Oct 24;13:1008301. doi: 10.3389/fendo.2022.1008301

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Copyright © 2022 Gu, Zeng, Ma, Zhang, Liu, Guo, Ruan, Chi, Zheng and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of CIMP and its association with clinical outcome. (A) Heatmap showing the DNA methylation pattern between CIMP (high-methylation) and nCIMP(low-methylation) using DNA methylation M-values. Kaplan-Meier curves between two epigenetic phenotypes regarding (B) OS (Overall survival) and (C) PFS (Progression free survival).