Skip to main content
. 2022 Oct 24;13:967989. doi: 10.3389/fimmu.2022.967989
DSBs double-strand DNA breaks
ROS reactive oxygen species
RNS reactive nitrogen species
DDR DNA-damage response
MRN Mre11-Rad50-Nbs1
ATM ataxia telangiectasia mutated
H2AX histone variant 2AX
NF-κB nuclear factor kappa-B
IL-1β interleukin-1β
IL-18 interleukin-18
NLRP3 nucleotide-binding oligomerization domain (NOD)-like receptors, pyrin domain-containing protein 3
AIM2 absent in melanoma 2
PAMPs pathogen-associated molecular patterns
DAMPs damage-associated molecular patterns
ASC apoptosis-associated speck-like protein containing a CARD
caspase cysteinyl aspartate specific proteinase
GSDMD gasdermin-D
LPS lipopolysaccharide
ETC electron transfer chain
TXNIP thioredoxin-interacting protein
Trx-1 thioredoxin-1
NAC N-acetylcysteine
mtDNA mitochondrial DNA
RIF Radiation-induced fibrosis
SGs stress granules
MSC mesenchymal stem cell