Table 1.
The demographic and clinical characteristics of both groups
| Item | Total (n = 42) (n %) |
Group 1 Acute hepatitis of unknown etiology (n = 24) (n %) |
Group 2 Acute hepatitis of identified etiology(n = 18) (n %) |
P value |
|---|---|---|---|---|
| Sex | 0.044* | |||
| Males | 26 (61.9%) | 18 (75%) | 8 (44.4%) | |
| Females | 16 (38.1%) | 6 (25%) | 10 (55.6%) | |
| Age (mean ± SD) | 34.55 ± 16.272 | 35.92 ± 17.177 | 32.72 ± 15.273 | 0.536 |
| Range | 14–72 | 16–72 | 14–64 | |
| Clinical presentations | ||||
| Jaundice | 39 (92.9%) | 24 (100%) | 15 (83.3%) | 0.038* |
| Dark urine | 26 (61.9%) | 19 (79.2%) | 7 (38.9%) | 0.008* |
| Abdominal pain | 22 (52.4%) | 15 (62.5%) | 7 (38.9%) | 0.129 |
| Fever | 21(50%) | 11 (45.8%) | 10 (55.6%) | 0.533 |
| Vomiting | 14 (33.3%) | 5 (20.8%) | 9 (50%) | 0.047* |
| Diarrhea | 5 (11.9%) | 5 (20.8%) | 0 (0%) | 0.039* |
| Bleeding | 3 (7.1%) | 2 (8.3%) | 1 (5.6%) | 0.729 |
| Encephalopathy | 14 (33.3%) | 7 (29.2%) | 7 (38.9%) | 0.508 |
| Grade I | 4 (9.5%) | |||
| Grade II | 1 (2.4%) | |||
| Grade III | 5 (11.9%) | |||
| Grade IV | 4 (9.5%) | |||
| Ascites | ||||
| No | 33 (78.6%) | 19 (79.2%) | 14 (77.8%) | 0.632 |
| Mild | 8 (19%) | 4 (16.7%) | 4 (22.2%) | |
| Moderate | 1 (2.4%) | 1 (4.2%) | 0 (0%) | |
| Course of hepatitis | ||||
| Acute hepatitis | 20 (47.6%) | 13 (54.2%) | 8 (44.4%) | 0.533 |
| Fulminant | 12 (28.6%) | 7 (29.2%) | 5 (27.8%) | |
| ACLF | 10 (23.8%) | 5 (20.8%) | 5 (27.8%) | |
| Duration of symptoms (days): median (IQR) | 14 (7.8) | 13.5(8) | 14(7) | 0.331 |
| Duration of hospitalization (days): mean ± SD | 12.81 ± 8.037 | 12.63 ± 8.144 | 13.06 ± 8.120 | 0.866 |
| Range | 3–30 | 3–30 | 4–30 | |
| Outcomes | ||||
| Alive | 32 (76.2%) | 18(75%) | 14(77.8%) | 0.834 |
| Death | 10 (23.8%) | 6 (25%) | 4 (22.2%) | |
ACLF acute-on-chronic liver failure
Both represent Significant p value
* Significantly different values