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. 2022 Sep 23;4(11):533–541. doi: 10.1253/circrep.CR-22-0095

Table 4.

Site of Major Bleeding in Patients With and Without Active Cancer

  All
(n=702)
With active cancer
(n=323)
Without active cancer
(n=379)
P value
All major bleeding 58 (8.3) 42 (13.0) 16 (4.2) <0.001
Specific site
 Gastrointestinal tract bleeding 25 (3.6) 18 (5.6) 7 (1.8) 0.008
 Genital bleeding 11 (1.6) 10 (3.1) 1 (0.3) 0.003
 Urinary tract bleeding 5 (0.7) 4 (1.2) 1 (0.3) 0.126
 Intracranial bleeding 4 (0.6) 2 (0.6) 2 (0.5) 0.873
 Respiratory bleeding 3 (0.4) 2 (0.6) 1 (0.3) 0.472
 Liver/gall bladder bleeding 2 (0.3) 1 (0.3) 1 (0.3) 0.910
 Postoperative bleeding triggered by DOACs 3 (0.4) 2 (0.6) 1 (0.3) 0.472
 Others 5 (0.7) 3 (0.9) 2 (0.5) 0.529

Unless indicated otherwise, data are presented as n (%). DOACs, direct oral anticoagulants.